Division of Basic Sciences, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
Cell Host Microbe. 2018 Nov 14;24(5):613-615. doi: 10.1016/j.chom.2018.10.014.
Though critical for preventing fatal sepsis, the mechanisms mediating the capture of bloodstream bacteria are incompletely understood. New work by Zeng et al. (2018) demonstrates that estrogen-regulated innate antibodies protect females and newborns from death following bloodstream infection with enteropathogenic Eschericia coli.
虽然对于预防致命性败血症至关重要,但介导血流细菌捕获的机制仍不完全清楚。曾等人的新研究(2018 年)表明,雌激素调节的固有抗体可保护女性和新生儿免受肠致病性大肠杆菌血流感染后的死亡。