Herms E, Kallischnigg G
Dept. Dermatologie, der Schering Aktiengesellschaft.
Z Hautkr. 1988 May 15;63(5):377-84.
In 3 controlled multi-center studies, 372 patients suffering from dermatomycoses were treated with isoconazole as cream, solution, and spray either once or twice daily. Neither with regard to the duration of healing nor the healing rates were observed statistically significant differences between the two modes of treatment. As to the forms of preparation, there were no differences of efficacy either. At the end of treatment, the cure rates amounted to 90-94%. Follow-up examinations carried out two weeks later gave no indications of relapses.
在3项对照多中心研究中,372名皮肤真菌病患者接受了异康唑乳膏、溶液和喷雾剂治疗,每天给药1次或2次。在两种治疗方式之间,无论是愈合持续时间还是愈合率,均未观察到统计学上的显著差异。至于制剂形式,疗效也没有差异。治疗结束时,治愈率达90%-94%。两周后进行的随访检查未发现复发迹象。