Burai Peter, Hajdu Andras, Manuel Felipe-Riveron Edgardo, Harangi Balazs
Annu Int Conf IEEE Eng Med Biol Soc. 2018 Jul;2018:49-52. doi: 10.1109/EMBC.2018.8512245.
In the past decades, the number of in vitro fertilization (IVF) procedures for the conception of a child has been rising continuously, however, the success rate of artificial insemination remained low. According to current statistics, large portion of unsuccessful IVF relates to some women' factors. As the directly related female organ, the proper investigation of the uterus has primary importance. Namely, visible markers may indicate inflammations or other negative effects that jeopardize successful implantation. The purpose of this study is to support the observability of the uterus from this aspect by providing computer-aided tools for the extraction of its wall from video hysteroscopy. As for methodology, fully convolutional neural networks (FCNNs) are used for the automatic segmentation of the video frames to determine the region of interest. We provide the necessary steps for the applicability of the general deep learning framework for this specific task. Moreover, we increase segmentation accuracy with applying ensemble-based approaches at two levels. First, the predictions of a given FCNN are aggregated for the overlapping regions of subimages, which are derived from the splitting of the original images. Next, the segmentation results of different FCNNs are fused via a weighted combination model; optimization for adjusting the weights are also provided. Based on our experimental results, we have achieved 91.56% segmentation accuracy regarding the recognition of the uterus wall.
在过去几十年中,用于受孕的体外受精(IVF)程序数量一直在持续上升,然而,人工授精的成功率仍然很低。根据目前的统计数据,大部分体外受精失败与某些女性因素有关。作为直接相关的女性器官,对子宫进行恰当的检查至关重要。也就是说,可见标志物可能表明存在炎症或其他危及成功着床的负面影响。本研究的目的是通过提供用于从视频宫腔镜检查中提取子宫壁的计算机辅助工具,从这方面支持子宫的可观察性。至于方法,全卷积神经网络(FCNN)用于对视频帧进行自动分割以确定感兴趣区域。我们提供了将通用深度学习框架应用于该特定任务的必要步骤。此外,我们通过在两个层面应用基于集成的方法提高分割精度。首先,对于从原始图像分割得到的子图像的重叠区域,聚合给定FCNN的预测结果。其次,通过加权组合模型融合不同FCNN的分割结果;还提供了用于调整权重的优化方法。基于我们的实验结果,在子宫壁识别方面我们实现了91.56%的分割精度。