Roy Subhrajit, Kiral-Kornek Isabell, Harrer Stefan
Annu Int Conf IEEE Eng Med Biol Soc. 2018 Jul;2018:2756-2759. doi: 10.1109/EMBC.2018.8512756.
In hospitals, physicians diagnose brain-related disorders such as epilepsy by analyzing electroencephalograms (EEG). However, manual analysis of EEG data requires highly trained clinicians or neurophysiologists and is a procedure that is known to have relatively low inter-rater agreement (IRA). Moreover, the volume of the data and rate at which new data is acquired makes interpretation a time-consuming, resource hungry, and expensive process. In contrast, automated analysis offers the potential to improve the quality of patient care by shortening the time to diagnosis, reducing manual error, and automatically detecting debilitating events. In this paper, we focus on one of the early decisions made in this process which is identifying whether an EEG session is normal or abnormal. Unlike previous approaches, we do not extract hand-engineered features but employ deep neural networks that automatically learn meaningful representations. We undertake a holistic study by exploring various pre-processing techniques and machine learning algorithms for addressing this problem and compare their performance. We have used the recently released "TUH Abnormal EEG Corpus" dataset for evaluating the performance of these algorithms. We show that modern deep gated recurrent neural networks achieve 3.47% better performance than previously reported results.
在医院中,医生通过分析脑电图(EEG)来诊断癫痫等与大脑相关的疾病。然而,脑电图数据的人工分析需要训练有素的临床医生或神经生理学家,而且这一过程的评分者间信度(IRA)相对较低。此外,数据量以及新数据的获取速度使得解读成为一个耗时、资源消耗大且成本高昂的过程。相比之下,自动分析有可能通过缩短诊断时间、减少人为错误以及自动检测衰弱事件来提高患者护理质量。在本文中,我们专注于这一过程中做出的早期决策之一,即识别一次脑电图检查是正常还是异常。与以往方法不同,我们不提取手工设计的特征,而是采用能自动学习有意义表征的深度神经网络。我们通过探索各种预处理技术和机器学习算法来解决这个问题,并对它们的性能进行比较,从而进行了一项全面的研究。我们使用了最近发布的“TUH异常脑电图语料库”数据集来评估这些算法的性能。我们表明,现代深度门控循环神经网络的性能比之前报道的结果提高了3.47%。