Biswal Dibyajyoti, Mollakazemi Mohammad Javad, Thyagarajan Sridevi, Evans Joyce, Patwardhan Abhijit
Annu Int Conf IEEE Eng Med Biol Soc. 2018 Jul;2018:2776-2779. doi: 10.1109/EMBC.2018.8512861.
Listening to music has been known to affect autonomic function of cardiovascular regulation. Baroreflex is a feedback control loop that uses rate changes of the heart in order to regulate beat by beat changes in blood pressure (BP). In this study, we used two approaches to compute measures of sensitivity of the baroreflex (BRS), a time domain sequence approach and frequency domain transfer functions. Subjects listened to slow and fast tempo songs during the study. Electrocardiogram (ECG) and non-invasive continuous BP were recorded in 14 subjects (7 males and females). From these signals, either beat by beat or equi-sampled in time RR intervals and systolic BP (SBP) were computed. BRS was then estimated using RR and SBP. Our results show that the sequence method consistently provided higher values of BRS than the transfer function method (up to two fold). The two measures were reasonably well correlated $( \mathrm {R}>0.84)$ during control and the slow song, but not during the fast song. The BRS was lower $( \sim 20$%) than control when listening to fast songs $( \mathrm {p}<0.005)$. These results show the effects of listening to songs on BRS changes, but also show that the two methods to estimate BRS, although reasonably correlated, do not always provide similar estimates of BRS.
众所周知，听音乐会影响心血管调节的自主功能。压力反射是一种反馈控制回路，它利用心脏的速率变化来调节逐搏的血压变化。在本研究中，我们使用了两种方法来计算压力反射敏感性（BRS）的指标，一种是时域序列法，另一种是频域传递函数法。在研究过程中，受试者聆听了慢节奏和快节奏的歌曲。记录了14名受试者（7名男性和7名女性）的心电图（ECG）和无创连续血压。从这些信号中，计算出逐搏或等时间采样的RR间期和收缩压（SBP）。然后使用RR和SBP来估计BRS。我们的结果表明，序列法始终比传递函数法提供更高的BRS值（高达两倍）。在对照和慢歌期间，这两种测量方法的相关性较好（R>0.84），但在快歌期间并非如此。听快歌时，BRS比对照时低（约20%）（p<0.005）。这些结果显示了听歌曲对BRS变化的影响，同时也表明，虽然两种估计BRS的方法相关性较好，但并不总是能提供相似的BRS估计值。
