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一种用于比较局部平均参考信号和公共平均参考信号的新型微脑电图电极接口。

A Novel µECoG Electrode Interface for Comparison of Local and Common Averaged Referenced Signals.

作者信息

Williams Ashley J, Trumpis Michael, Bent Brinnae, Chiang Chia-Han, Viventi Jonathan

出版信息

Annu Int Conf IEEE Eng Med Biol Soc. 2018 Jul;2018:5057-5060. doi: 10.1109/EMBC.2018.8513432.


DOI:10.1109/EMBC.2018.8513432
PMID:30441477
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7478123/
Abstract

Micro-electrocorticography (µECoG) is a minimally invasive neural interface that allows for recording from the surface of the brain with high spatial and temporal resolution [1], [2]. However, discerning multi-unit and local field potential (LFP) activity with potentially highly-correlated signals across a dense µECoG array can be challenging. Here we describe a novel µECoG design to compare the effect of referencing recordings to a local reference electrode and common average referencing (CAR). The filtering effect and the significant increase in signal to noise ratio of the evoked response (ESNR) can be seen after re-referencing for both types of referencing. In a preliminary analysis, re-referencing the µECoG signals can increase recording performance at high contact densities in the auditory cortex. This also provides promising evidence for a versatile in-house fabricated µECoG electrode.

摘要

微皮层脑电图(µECoG)是一种微创神经接口,能够以高空间和时间分辨率从大脑表面进行记录[1,2]。然而,在密集的µECoG阵列中辨别具有潜在高度相关信号的多单元和局部场电位(LFP)活动可能具有挑战性。在此,我们描述了一种新型µECoG设计,以比较将记录参考至局部参考电极和公共平均参考(CAR)的效果。对于这两种参考类型,重新参考后均可观察到滤波效果以及诱发反应的信噪比显著增加(ESNR)。在初步分析中,对µECoG信号进行重新参考可提高听觉皮层中高接触密度下的记录性能。这也为一种通用的内部制造的µECoG电极提供了有前景的证据。

相似文献

[1]
A Novel µECoG Electrode Interface for Comparison of Local and Common Averaged Referenced Signals.

Annu Int Conf IEEE Eng Med Biol Soc. 2018-7

[2]
Mapping the fine structure of cortical activity with different micro-ECoG electrode array geometries.

J Neural Eng. 2017-6-9

[3]
Progress in the Field of Micro-Electrocorticography.

Micromachines (Basel). 2019-1-17

[4]
A cortical recording platform utilizing microECoG electrode arrays.

Annu Int Conf IEEE Eng Med Biol Soc. 2007

[5]
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[6]
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[7]
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[8]
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[9]
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[10]
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引用本文的文献

[1]
Generalizable spelling using a speech neuroprosthesis in an individual with severe limb and vocal paralysis.

Nat Commun. 2022-11-8

[2]
A modular high-density μECoG system on macaque vlPFC for auditory cognitive decoding.

J Neural Eng. 2020-7-10

本文引用的文献

[1]
In vitro assessment of long-term reliability of low-cost μECoG arrays.

Annu Int Conf IEEE Eng Med Biol Soc. 2016-8

[2]
Bioresorbable silicon electronics for transient spatiotemporal mapping of electrical activity from the cerebral cortex.

Nat Mater. 2016-7

[3]
A low-cost, multiplexed μECoG system for high-density recordings in freely moving rodents.

J Neural Eng. 2016-4

[4]
Towards large-scale, human-based, mesoscopic neurotechnologies.

Neuron. 2015-4-8

[5]
NeuroGrid: recording action potentials from the surface of the brain.

Nat Neurosci. 2014-12-22

[6]
How local is the local field potential?

Neuron. 2011-12-8

[7]
Flexible, foldable, actively multiplexed, high-density electrode array for mapping brain activity in vivo.

Nat Neurosci. 2011-11-13

[8]
Optimal spacing of surface electrode arrays for brain-machine interface applications.

J Neural Eng. 2010-3-2

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