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本文引用的文献

1
The pursuit of balance: An overview of covariate-adaptive randomization techniques in clinical trials.对平衡的追求：临床试验中协变量自适应随机化技术概述
Contemp Clin Trials. 2015 Nov;45(Pt A):21-5. doi: 10.1016/j.cct.2015.07.011. Epub 2015 Aug 2.
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Palliative care in the management of advanced HIV/AIDS.晚期艾滋病毒/艾滋病管理中的姑息治疗。
Prim Care. 2011 Jun;38(2):311-26, ix. doi: 10.1016/j.pop.2011.03.010.
3
What palliative care-related problems do patients experience at HIV diagnosis? A systematic review of the evidence.艾滋病诊断时患者经历了哪些姑息治疗相关问题？系统评价证据。
J Pain Symptom Manage. 2011 Nov;42(5):734-53. doi: 10.1016/j.jpainsymman.2011.02.014. Epub 2011 May 26.
4
Adverse health effects for individuals who move between HIV care centers.在艾滋病护理中心之间转移的个人的健康不良影响。
J Acquir Immune Defic Syndr. 2011 May 1;57(1):51-4. doi: 10.1097/QAI.0b013e318214feee.
5
Why health care is going home.为何医疗正在回归家庭。
N Engl J Med. 2010 Oct 28;363(18):1690-1. doi: 10.1056/NEJMp1000401. Epub 2010 Oct 20.
6
Symptoms are highly prevalent among HIV outpatients and associated with poor adherence and unprotected sexual intercourse.症状在 HIV 门诊患者中非常普遍，与较差的依从性和无保护的性行为有关。
Sex Transm Infect. 2010 Dec;86(7):520-4. doi: 10.1136/sti.2009.038505. Epub 2010 Jun 15.
7
Successful models of comprehensive care for older adults with chronic conditions: evidence for the Institute of Medicine's "retooling for an aging America" report.成功的慢性病老年综合护理模式：为美国医学研究所“为老龄化美国重新装备”报告提供证据。
J Am Geriatr Soc. 2009 Dec;57(12):2328-37. doi: 10.1111/j.1532-5415.2009.02571.x.
8
Palliative Access Through Care at Home: experiences with an urban, geriatric home palliative care program.通过居家护理实现姑息治疗可及性：一项城市老年居家姑息治疗项目的经验
J Am Geriatr Soc. 2009 Oct;57(10):1925-31. doi: 10.1111/j.1532-5415.2009.02452.x. Epub 2009 Aug 21.
9
Patient reports of symptoms and their treatment at three palliative care projects servicing individuals with HIV/AIDS.针对感染艾滋病毒/艾滋病患者的三个姑息治疗项目中患者的症状报告及其治疗情况。
J Pain Symptom Manage. 2005 Nov;30(5):408-17. doi: 10.1016/j.jpainsymman.2005.04.011.
10
You want to measure coping but your protocol's too long: consider the brief COPE.你想测量应对方式，但你的方案太长：可以考虑使用简易应对方式问卷。
Int J Behav Med. 1997;4(1):92-100. doi: 10.1207/s15327558ijbm0401_6.

一项社区导航干预改善艾滋病毒感染者及其他合并症患者幸福感的随机临床试验。

Randomized clinical trial of a community navigation intervention to improve well-being in persons living with HIV and other co-morbidities.

作者信息

Webel Allison, Prince-Paul Maryjo, Ganocy Stephen, DiFranco Evelina, Wellman Charles, Avery Ann, Daly Barbara, Slomka Jacquelyn

机构信息

a Case Western Reserve University (CWRU) School of Nursing , Cleveland , OH , USA.

b Hospice of the Western Reserve , Cleveland , OH , USA.

出版信息

AIDS Care. 2019 May;31(5):529-535. doi: 10.1080/09540121.2018.1546819. Epub 2018 Nov 15.

DOI:10.1080/09540121.2018.1546819
PMID:30442033
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6408262/
Abstract

Long-term survival of people living with HIV (PLWH) is associated with the development of co-morbid conditions and need for symptom management and other efforts to enhance quality of life. We conducted a longitudinal, randomized trial over 36 months to evaluate the effect of a community-based navigator intervention to provide early palliative care to 179 PLWH and other chronic conditions. Outcomes included quality of life, symptom management, coping ability, social support, self-management, and completion of advance directives. Data were analyzed using SAS mixed effects model repeat measurement. Our navigator program showed variable improvement over time of three outcome variables, self-blame, symptom distress, and HIV self-management. However, the program did not improve overall quality of life, social support, or completion of advance directives.

摘要

艾滋病毒感染者（PLWH）的长期生存与共病状况的发展以及症状管理和其他提高生活质量的努力需求相关。我们进行了一项为期36个月的纵向随机试验，以评估基于社区的导航干预措施对179名艾滋病毒感染者和其他慢性病患者提供早期姑息治疗的效果。结果包括生活质量、症状管理、应对能力、社会支持、自我管理以及预先指示的完成情况。使用SAS混合效应模型重复测量对数据进行分析。我们的导航项目在三个结果变量（自责、症状困扰和艾滋病毒自我管理）上随时间显示出不同程度的改善。然而，该项目并未改善总体生活质量、社会支持或预先指示的完成情况。