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一项比较置入支架与未置入支架的安德森-海恩斯离断性肾盂成形术后结局的随机对照试验。

A Randomized Control Trial Comparing Outcome after Stented and Nonstented Anderson-Hynes Dismembered Pyeloplasty.

作者信息

Nagdeve Nilesh G, Bhingare Pravin D, Sarawade Prashant

机构信息

Department of Paediatric Surgery, Government Medical College, Nagpur, Maharashtra, India.

Department of General Surgery, Government Medical College, Nagpur, Maharashtra, India.

出版信息

J Indian Assoc Pediatr Surg. 2018 Oct-Dec;23(4):186-191. doi: 10.4103/jiaps.JIAPS_58_17.

Abstract

AIM

The aim of the study was to compare the efficacy and postoperative complications of stented and nonstented open pediatric dismembered pyeloplasty for ureteropelvic junction (UPJ) obstruction.

SETTINGS AND DESIGN

A balanced, parallel group, prospective randomized controlled trial comparing stented and nonstented Anderson-Hynes Dismembered Pyeloplasty.

SUBJECTS AND METHODS

It included 42 children who required Anderson-Hynes dismembered pyeloplasty for UPJ obstruction (UPJO). Patients were randomized into stented (double "J" [DJ] stent) and nonstented pyeloplasty groups. The intraoperative and postoperative course was compared. Both groups were analyzed for problems such as dysuria, frequency, pain, hematuria and urinary tract infection, and postoperative renal status.

STATISTICAL ANALYSIS

Mann-Whitney U-test, Fisher's exact test, Student's -tests, and Chi-squared test were used.

RESULTS

Surgical duration was significantly shorter for the nonstented group as compared to the stented group (60.4 ± 6.49 min vs. 78.9 ± 8.17 min). The intraoperative negotiation of DJ stent was troublesome in 21.7% patients belonging to the stented group. The hospital stay was comparable in both groups (4.67 ± 1.9 vs. 4.28 ± 0.67 days). Patients in stented group had experienced dysuria, loin pain, lower abdominal spasmodic pain, and frequency significantly higher than nonstented group. However, the other problems such as fever, hematuria, and urinary tract infections were more common in stented group, but the difference was not statistically significant. There was no difference in resolution of hydronephrosis in both groups.

CONCLUSIONS

There is no statistically significant difference in resolution of hydronephrosis following nonstented or stented dismembered pyeloplasty in children with UPJO. However, the patient is more symptomatic due to stent in the postoperative period.

摘要

目的

本研究旨在比较置入支架与未置入支架的开放性小儿离断式肾盂成形术治疗肾盂输尿管连接部(UPJ)梗阻的疗效及术后并发症。

设置与设计

一项平衡、平行组、前瞻性随机对照试验,比较置入支架与未置入支架的安德森-海因斯离断式肾盂成形术。

研究对象与方法

纳入42例因UPJ梗阻(UPJO)需行安德森-海因斯离断式肾盂成形术的儿童。患者被随机分为置入支架(双“J”[DJ]支架)组和未置入支架的肾盂成形术组。比较术中及术后过程。分析两组患者尿痛、尿频、疼痛、血尿和尿路感染等问题以及术后肾脏状况。

统计分析

采用曼-惠特尼U检验、费舍尔精确检验、学生t检验和卡方检验。

结果

与置入支架组相比,未置入支架组的手术时间明显更短(60.4±6.49分钟对78.9±8.17分钟)。置入支架组21.7%的患者术中DJ支架置入困难。两组的住院时间相当(4.67±1.9天对4.28±0.67天)。置入支架组患者的尿痛、腰痛、下腹部痉挛性疼痛和尿频发生率明显高于未置入支架组。然而,发热、血尿和尿路感染等其他问题在置入支架组更常见,但差异无统计学意义。两组肾积水的缓解情况无差异。

结论

对于患有UPJO的儿童,未置入支架或置入支架后的离断式肾盂成形术在肾积水缓解方面无统计学显著差异。然而,术后患者因支架导致的症状更明显。

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