Freie Universität Berlin, Institut für Biologie, Berlin, Germany.
J Comp Neurol. 2019 Apr 15;527(6):1027-1038. doi: 10.1002/cne.24583. Epub 2018 Dec 11.
In this study, we describe a cluster of tyraminergic/octopaminergic neurons in the lateral dorsal deutocerebrum of desert locusts (Schistocerca gregaria) with descending axons to the abdominal ganglia. In the locust, these neurons synthesize octopamine from tyramine stress-dependently. Electrophysiological recordings in locusts reveal that they respond to mechanosensory touch stimuli delivered to various parts of the body including the antennae. A similar cluster of tyraminergic/octopaminergic neurons was also identified in the American cockroach (Periplaneta americana) and the pink winged stick insect (Sipyloidea sipylus). It is suggested that these neurons release octopamine in the ventral nerve cord ganglia and, most likely, convey information on arousal and/or stressful stimuli to neuronal circuits thus contributing to the many actions of octopamine in the central nervous system.
在这项研究中，我们描述了沙漠蝗（Schistocerca gregaria） lateral dorsal deutocerebrum 中一群具有下行轴突到腹部神经节的 tyraminergic/octopaminergic 神经元。在蝗虫中，这些神经元应激依赖性地从 tyramine 合成章鱼胺。在蝗虫中的电生理记录表明，它们对身体各部位（包括触角）的机械感觉触摸刺激有反应。在美洲蟑螂（Periplaneta americana）和粉翅竹节虫（Sipyloidea sipylus）中也发现了类似的 tyraminergic/octopaminergic 神经元群。据推测，这些神经元在腹神经索神经节中释放章鱼胺，并且很可能将唤醒和/或应激刺激的信息传递给神经元回路，从而有助于章鱼胺在中枢神经系统中的许多作用。
