Department of Public Health, Erasmus MC, University Medical Center Rotterdam, Rotterdam, The Netherlands.
Netherlands Leprosy Relief, India Country Office, New Delhi, India.
Trop Med Int Health. 2019 Feb;24(2):155-165. doi: 10.1111/tmi.13182. Epub 2018 Dec 6.
The WHO recommends inclusion of post-exposure chemoprophylaxis with single-dose rifampicin in national leprosy control programmes. The objective was to estimate the cost of leprosy services at primary care level in two different public-health settings.
Ingredient-based costing was performed in eight primary health centres (PHCs) purposively selected in the Union Territory of Dadra and Nagar Haveli (DNH) and the Umbergaon block of Valsad district, Gujarat, India. All costs were bootstrapped, and to estimate the variation in total cost under uncertainty, a univariate sensitivity analysis was performed.
The mean annual cost of providing leprosy services was USD 29 072 in the DNH PHC (95% CI: 22 125-36 020) and USD 11 082 in Umbergaon (95% CI: 8334-13 830). The single largest cost component was human resources: 79% in DNH and 83% in Umbergaon. The unit cost for screening the contact of a leprosy patient was USD 1 in DNH (95% CI: 0.8-1.2) and USD 0.3 in Umbergaon (95% CI: 0.2-0.4). In DNH, the unit cost of delivering single-dose of rifampicin (SDR) as chemoprophylaxis for contacts was USD 2.9 (95% CI: 2.5-3.7).
The setting with an enhanced public-health financing system invests more in leprosy services than a setting with fewer financial resources. In terms of leprosy visits, the enhanced public-health system is hardly more expensive than the non-enhanced public-health system. The unit cost of contact screening is not high, favouring its sustainability in the programme.
世界卫生组织建议在国家麻风控制规划中纳入单剂利福平的接触后化学预防。目的是估计在两个不同公共卫生环境下基层医疗水平的麻风服务成本。
在印度古吉拉特邦的达德拉和纳加尔哈维利联合属地(DNH)和乌姆巴琼的瓦尔萨德区,有 8 个初级保健中心(PHC)被有目的地选中,进行基于成分的成本核算。所有成本都进行了自举,为了在不确定的情况下估计总成本的变化,进行了单变量敏感性分析。
在 DNH PHC 中,提供麻风服务的年平均成本为 29072 美元(95%CI:22125-36020),在 Umbergaon 为 11082 美元(95%CI:8334-13830)。最大的成本构成部分是人力资源:DNH 占 79%,Umbergaon 占 83%。对麻风病患者接触者进行筛查的单位成本为 DNH 中的 1 美元(95%CI:0.8-1.2)和 Umbergaon 中的 0.3 美元(95%CI:0.2-0.4)。在 DNH 中,为接触者提供单剂量利福平(SDR)作为化学预防的单位成本为 2.9 美元(95%CI:2.5-3.7)。
拥有强化公共卫生融资系统的环境比资源较少的环境在麻风服务方面投入更多。就麻风病就诊而言,强化公共卫生系统的费用并不比非强化公共卫生系统高。接触者筛查的单位成本不高,有利于该方案的可持续性。