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四种治疗不稳定型转子间骨折方法效果的比较:网状荟萃分析。

Comparison of effects of four treatment methods for unstable intertrochanteric fractures: A network meta-analysis.

机构信息

Department of Orthopedics, Ningbo Yinzhou Second Hospital, Ningbo Zhejiang, 315100, China.

Department of Orthopedics, Ningbo Yinzhou Second Hospital, Ningbo Zhejiang, 315100, China.

出版信息

Int J Surg. 2018 Dec;60:173-181. doi: 10.1016/j.ijsu.2018.11.011. Epub 2018 Nov 13.

Abstract

PURPOSE

The optimal internal fixation device for unstable intertrochanteric fracture remains a matter of controversy. By performing network meta-analysis, we developed a ranking of the following four surgical methods: proximal femoral nail antirotation, InterTan nail, gamma nail (GN) and sliding hip screws. We compare the complication rates in patients with unstable intertrochanteric fractures.

MATERIALS AND METHODS

After an exhaustive search of MEDLINE, EMBASE and the Cochrane Central Register of Controlled Trials for relevant studies, randomized controlled trials meeting selection criteria were entered into our network meta-analysis. Statistical analyses were conducted using Stata software, version 13.0 (Stata Corporation, College Station, Texas, USA).

RESULTS

We included 12 randomized controlled trials. Compared to Sliding hip screw, there were no substantial differences in rates of complications in unstable intertrochanteric fractures patient undergoing various treatments (all p > 0.05). Nevertheless, the surface under the cumulative ranking curve (SUCRA) for GN (80.6%) was significantly higher than those of the other three methods.

CONCLUSION

GN had the highest probability of reducing the total incidence of complications among the four interventions for treating unstable intertrochanteric fractures.

摘要

目的

不稳定型转子间骨折的最佳内固定装置仍存在争议。通过进行网络荟萃分析,我们对以下四种手术方法(股骨近端防旋髓内钉、InterTan 钉、Gamma 钉和滑动髋螺钉)进行了排名,并比较了不稳定型转子间骨折患者的并发症发生率。

材料和方法

在 MEDLINE、EMBASE 和 Cochrane 对照试验中心注册数据库中进行全面检索,纳入符合选择标准的随机对照试验进行网络荟萃分析。使用 Stata 软件(Stata Corporation,德克萨斯州 College Station)进行统计分析,版本为 13.0。

结果

共纳入 12 项随机对照试验。与滑动髋螺钉相比,接受不同治疗的不稳定型转子间骨折患者的并发症发生率没有显著差异(均 p>0.05)。然而,Gamma 钉的累积排序曲线下面积(SUCRA)(80.6%)明显高于其他三种方法。

结论

在治疗不稳定型转子间骨折的四种干预措施中,Gamma 钉降低并发症总发生率的可能性最高。

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