Research Institute for Primary Care and Health Sciences, Keele University, Keele, UK.
Rheumatology (Oxford). 2018 Aug 1;57(suppl_6):vi29-vi34. doi: 10.1093/rheumatology/key200.
Axial SpA (axSpA) can affect diverse elements of an individual's life. The areas affected can be much more wide-ranging than the historical medical model of SpA, causing increased disease activity (pain and stiffness) and disability (reduced range of movement and physical function). A more holistic view of the individual results in the realization that many other areas of life can be adversely affected by axSpA, from the ability to work effectively and function socially, to effects on quality of life and the onset of worsening fatigue or mood disturbance. A good understanding of these areas outside the medical model allows for an improved understanding of the overall life impact of axSpA. This highlights the importance of understanding how to measure these elements of life using patient-reported outcome measures that can truly reflect an individual's experience of axSpA. These measures can then provide a better insight into the risks and benefits of interventions and medications used to treat axSpA.
中轴型脊柱关节炎（axSpA）可影响个体生活的多个方面。受影响的部位可能比既往 SpA 的医学模型所涵盖的范围更广，从而导致疾病活动度增加（疼痛和僵硬）和残疾（运动范围和身体功能降低）。对个体的更全面的认识使人们意识到，许多其他生活领域也会受到 axSpA 的不利影响，包括有效工作和社交的能力，以及生活质量和疲劳或情绪紊乱恶化的发生。更好地了解医学模型之外的这些领域，可以更好地了解 axSpA 对整体生活的影响。这凸显了理解如何使用患者报告的结果测量来衡量这些生活要素的重要性，这些结果测量能够真实地反映个体 axSpA 的体验。这些测量方法可以更好地了解用于治疗 axSpA 的干预措施和药物的风险和获益。
