Department of Pharmacognosy and Pharmaceutical Botany, Faculty of Pharmaceutical Sciences, Prince of Songkla University, Hat-Yai, Songkhla, Thailand.
Department of Biology, King Mongkut's Institute of Technology, Ladkrabang, Bangkok, Thailand.
Nat Prod Res. 2020 Mar;34(5):710-713. doi: 10.1080/14786419.2018.1493589. Epub 2018 Nov 16.
The correlation between the allocation of trisoxazole macrolides in the capitums, appendages, and bases of the sponge cf. and the surface-attached bacteria on the corresponding parts was examined. The kabiramide contents were highest in the capitums, followed by the appendages and bases. Conversely, direct counts of cultivable surface-attached bacteria showed that the bacteria aggregate more densely on the surfaces of the bases. This suggested the repelling effects of the kabiramides against the fouling bacteria, particularly on the capitums and appendages. Twenty-two bacterial strains were isolated and identified to 15 species; however, none has shown the potentials as a producer of any secondary metabolites in the sponge .
考察了海绵 cf. 的顶部、附属物和基部的三唑大环内酯的分配与相应部位表面附着细菌之间的相关性。卡比拉米德含量在顶部最高,其次是附属物和基部。相反,可培养表面附着细菌的直接计数表明,细菌在基部表面更密集地聚集。这表明卡比拉米德对污垢细菌具有排斥作用,特别是在顶部和附属物上。分离并鉴定了 22 株细菌,鉴定为 15 个种;然而,没有一种显示出海绵 中任何次生代谢产物的产生潜力。