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尼龙球囊硬度对主动脉内球囊阻断效率的影响。

The influence of the nylon balloon stiffness on the efficiency of the intra-aortic balloon occlusion.

机构信息

Institute of Structural Engineering, Poznań University of Technology, Poznań, Poland.

Department of Vascular and Endovascular Surgery, Angiology, and Phlebology, Poznań University of Medical Sciences, Poznań, Poland.

出版信息

Int J Numer Method Biomed Eng. 2019 Apr;35(4):e3173. doi: 10.1002/cnm.3173. Epub 2019 Jan 9.

DOI:10.1002/cnm.3173
PMID:30447053
Abstract

In interventional procedures, the balloon inflation is used to occlude the artery and thus reduce bleeding. There is no practically accepted measure of the procedure efficiency. A finite element method model with state-of-the-art modelling techniques was built in order to predict the occlusion levels under the influence of different balloon inflation and its material stiffness. The geometries of a healthy human thoracic aorta and an occlusion balloon were idealized. The non-linear constitutive material of Gasser-Ogden-Holzapfel model was employed for the thoracic aorta; the balloon was model as the hyperelastic model. The realistic physiological blood pressure and the balloon inflation pressures were applied to simulate the different occlusion levels. The final outcome shows an important influence of the material stiffness on the balloon deformation and thus the occlusion efficiency.

摘要

在介入性手术中,使用球囊充气来阻塞动脉,从而减少出血。目前还没有一种实用的方法可以衡量手术的效率。为了预测不同球囊充气和材料刚度对闭塞程度的影响,建立了一个具有先进建模技术的有限元方法模型。理想化了健康的人体胸主动脉和闭塞球囊的几何形状。采用 Gasser-Ogden-Holzapfel 模型的非线性本构材料对胸主动脉进行建模;球囊被建模为超弹性模型。施加真实的生理血压和球囊充气压力来模拟不同的闭塞程度。最终结果表明,材料刚度对球囊变形和闭塞效率有重要影响。

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