Li Tao, Zhang Zhuo, Wang Wenyuan, Mao Aijia, Chen Yu, Xiong Yan, Gao Fei
College of Mechanical Engineering, Sichuan University, Chengdu 610065, China.
Chengdu Neurotrans Medical Technology Co., Ltd., Chengdu 610065, China.
J Funct Biomater. 2023 Jun 5;14(6):312. doi: 10.3390/jfb14060312.
A balloon dilatation catheter is a vital tool in percutaneous transluminal angioplasty. Various factors, including the material used, influence the ability of different types of balloons to navigate through lesions during delivery.
Thus far, numerical simulation studies comparing the impacts of different materials on the trackability of balloon catheters has been limited. This project seeks to unveil the underlying patterns more effectively by utilizing a highly realistic balloon-folding simulation method to compare the trackability of balloons made from different materials.
Two materials, nylon-12 and Pebax, were examined for their insertion forces via a bench test and a numerical simulation. The simulation built a model identical to the bench test's groove and simulated the balloon's folding process prior to insertion to better replicate the experimental conditions.
In the bench test, nylon-12 demonstrated the highest insertion force, peaking at 0.866 N, significantly outstripping the 0.156 N force exhibited by the Pebax balloon. In the simulation, nylon-12 experienced a higher level of stress after folding, while Pebax had demonstrated a higher effective strain and surface energy density. In terms of insertion force, nylon-12 was higher than Pebax in specific areas.
nylon-12 exerts greater pressure on the vessel wall in curved pathways when compared to Pebax. The simulated insertion forces of nylon-12 align with the experimental results. However, when using the same friction coefficient, the difference in insertion forces between the two materials is minimal. The numerical simulation method used in this study can be used for relevant research. This method can assess the performance of balloons made from diverse materials navigating curved paths and can yield more precise and detailed data feedback compared to benchtop experiments.
球囊扩张导管是经皮腔内血管成形术中的重要工具。包括所用材料在内的各种因素会影响不同类型球囊在输送过程中穿过病变的能力。
迄今为止，比较不同材料对球囊导管可跟踪性影响的数值模拟研究有限。本项目旨在通过使用高度逼真的球囊折叠模拟方法来比较不同材料制成的球囊的可跟踪性，从而更有效地揭示潜在模式。
通过台架试验和数值模拟研究了尼龙-12和Pebax这两种材料的插入力。该模拟构建了一个与台架试验凹槽相同的模型，并模拟了插入前球囊的折叠过程，以更好地复制实验条件。
在台架试验中，尼龙-12表现出最高的插入力，峰值为0.866 N，明显超过Pebax球囊所表现出的0.156 N的力。在模拟中，尼龙-12折叠后承受的应力水平更高，而Pebax表现出更高的有效应变和表面能密度。在插入力方面，尼龙-12在特定区域高于Pebax。
与Pebax相比，尼龙-12在弯曲路径中对血管壁施加的压力更大。尼龙-12的模拟插入力与实验结果一致。然而，当使用相同的摩擦系数时，两种材料之间的插入力差异最小。本研究中使用的数值模拟方法可用于相关研究。该方法可以评估由不同材料制成的球囊在弯曲路径中的性能，并且与台式实验相比，可以产生更精确和详细的数据反馈。
