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利用休克指数预测产后出血患者的产妇结局。

Use of the shock index to predict maternal outcomes in women referred for postpartum hemorrhage.

机构信息

Department of Obstetrics and Gynecology, Korea University College of Medicine, Seoul, South Korea.

出版信息

Int J Gynaecol Obstet. 2019 Feb;144(2):221-224. doi: 10.1002/ijgo.12714. Epub 2018 Dec 10.

Abstract

OBJECTIVE

To evaluate the clinical significance of various vital signs in women referred for postpartum hemorrhage (PPH).

METHODS

This retrospective study included patients with primary PPH who were referred to Korea University Medical Center, Ansan, between January 1, 2004, and December 31, 2016. We analyzed data for systolic and diastolic blood pressure, heart rate, and shock index (heart rate divided by systolic blood pressure) at time of arrival. Significant morbidity, such as massive transfusion, invasive procedures, and admission to the intensive care unit were reviewed. We used the area under the receiver operating characteristic curve (AUROC) for each vital sign to predict adverse maternal  outcomes. Sensitivity, specificity, and negative and positive predictive values were assessed.

RESULTS

118 women with PPH were identified. The shock index had the highest AUROC to predict massive transfusion (0.815, 95% confidence interval [CI] 0.727-0.883). A shock index greater than 0.9 had 93.8% (95% CI 69.8-99.8) sensitivity and 51.2% (35.1-67.1) specificity for prediction of massive transfusion, and 93.6% (78.6-99.2) sensitivity and 31.0% (15.3-50.8) specificity for prediction of invasive procedures.

CONCLUSION

The shock index has significant ability to predict adverse outcomes of PPH compared with other initial vital signs when patients are referred.

摘要

目的

评估因产后出血(PPH)而就诊的女性的各种生命体征的临床意义。

方法

本回顾性研究纳入了 2004 年 1 月 1 日至 2016 年 12 月 31 日期间因原发性 PPH 而转诊至韩国大学安山医疗中心的患者。我们分析了就诊时的收缩压和舒张压、心率和休克指数(心率除以收缩压)的数据。回顾了大量输血、有创操作和入住重症监护病房等显著发病率。我们使用每个生命体征的接受者操作特征曲线(AUROC)来预测不良的产妇结局。评估了敏感性、特异性、阴性和阳性预测值。

结果

共确定了 118 例 PPH 患者。休克指数对预测大量输血的 AUROC 最高(0.815,95%置信区间 [CI] 0.727-0.883)。休克指数大于 0.9 对大量输血的预测有 93.8%(95%CI 69.8-99.8)的敏感性和 51.2%(35.1-67.1)的特异性,对有创操作的预测有 93.6%(78.6-99.2)的敏感性和 31.0%(15.3-50.8)的特异性。

结论

与其他初始生命体征相比,休克指数在患者就诊时对 PPH 的不良结局有显著的预测能力。

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