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实现风湿学目标治疗策略的挑战。

Challenges in Implementing Treat-to-Target Strategies in Rheumatology.

机构信息

Division of Rheumatology, Brigham and Women's Hospital, 60 Fenwood Road, Boston, MA 02115, USA.

Division of Rheumatology, Brigham and Women's Hospital, 60 Fenwood Road, Boston, MA 02115, USA; Division of Pharmacoepidemiology, Brigham and Women's Hospital, 60 Fenwood Road, Boston, MA 02115, USA.

出版信息

Rheum Dis Clin North Am. 2019 Feb;45(1):101-112. doi: 10.1016/j.rdc.2018.09.007.

DOI:10.1016/j.rdc.2018.09.007
PMID:30447739
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8491430/
Abstract

Despite evidence that treat-to-target (TTT) approaches lead to better disease outcomes in RA, TTT is not widely implemented in rheumatology clinics in North America. This article discusses the barriers (including access to care, patient and physician factors, and systems issues) to implementing TTT in the clinic, and proposes possible solutions and future research directions.

摘要

尽管有证据表明,达标治疗(Treat-to-Target,TTT)方法可改善类风湿关节炎(rheumatoid arthritis,RA)的疾病结局,但在北美的风湿科诊所中,TTT 并未广泛实施。本文讨论了在临床实践中实施 TTT 的障碍(包括获得医疗服务的机会、患者和医生因素以及系统问题),并提出了可能的解决方案和未来的研究方向。

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Mobile Apps for Individuals With Rheumatoid Arthritis: A Systematic Review.类风湿关节炎患者的移动应用程序:系统评价。
J Clin Rheumatol. 2019 Apr;25(3):133-141. doi: 10.1097/RHU.0000000000000800.
2
Treat to target, remission and low disease activity in SLE.系统性红斑狼疮的达标治疗、缓解及低疾病活动度
Best Pract Res Clin Rheumatol. 2017 Jun;31(3):342-350. doi: 10.1016/j.berh.2017.09.009. Epub 2017 Oct 13.
3
Standardizing and personalizing the treat to target (T2T) approach for rheumatoid arthritis using the Patient-Reported Outcomes Measurement Information System (PROMIS): baseline findings on patient-centered treatment priorities.使用患者报告结局测量信息系统(PROMIS)对类风湿关节炎的达标治疗(T2T)方法进行标准化和个性化:以患者为中心的治疗优先级的基线研究结果
Clin Rheumatol. 2017 Aug;36(8):1729-1736. doi: 10.1007/s10067-017-3731-5. Epub 2017 Jun 26.
4
Low disease activity (DAS28≤3.2) reduces the risk of first cardiovascular event in rheumatoid arthritis: a time-dependent Cox regression analysis in a large cohort study.低疾病活动度(DAS28≤3.2)可降低类风湿关节炎患者首发心血管事件风险:一项大型队列研究中的时间依赖性 Cox 回归分析。
Ann Rheum Dis. 2017 Oct;76(10):1693-1699. doi: 10.1136/annrheumdis-2016-210997. Epub 2017 Jun 12.
5
Rheumatoid Arthritis Patients' Motivations for Accepting or Resisting Disease-Modifying Antirheumatic Drug Treatment Regimens.类风湿关节炎患者接受或抵制疾病修正抗风湿药物治疗方案的动机。
Arthritis Care Res (Hoboken). 2018 Apr;70(4):533-541. doi: 10.1002/acr.23301. Epub 2018 Mar 11.
6
Implementation of Treat-to-Target in Rheumatoid Arthritis Through a Learning Collaborative: Results of a Randomized Controlled Trial.通过学习合作实现类风湿关节炎的达标治疗:一项随机对照试验的结果。
Arthritis Rheumatol. 2017 Jul;69(7):1374-1380. doi: 10.1002/art.40111. Epub 2017 May 31.
7
Management of Acute and Recurrent Gout: A Clinical Practice Guideline From the American College of Physicians.急性和复发性痛风管理:美国医师学院临床实践指南。
Ann Intern Med. 2017 Jan 3;166(1):58-68. doi: 10.7326/M16-0570. Epub 2016 Nov 1.
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Treat-to-target (T2T) recommendations for gout.痛风的达标治疗(T2T)推荐。
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2016 updated EULAR evidence-based recommendations for the management of gout.2016 年更新的 EULAR 痛风管理循证建议。
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Rheum Dis Clin North Am. 2016 May;42(2):219-37. doi: 10.1016/j.rdc.2016.01.010. Epub 2016 Mar 17.