Department of Internal Medicine, Division of Cardiology, Northwestern University, Feinberg School of Medicine, Chicago, IL, USA.
Department of Internal Medicine, Division of Cardiology, Northwestern University, Feinberg School of Medicine, Chicago, IL, USA.
Heart Fail Clin. 2019 Jan;15(1):9-18. doi: 10.1016/j.hfc.2018.08.002.
Heart failure with preserved ejection fraction (HFpEF) is an increasingly prevalent condition, particularly in women. Comorbidities, including older age, obesity, diabetes mellitus, hypertension, and hyperlipidemia, are risk factors and define phenotypic profiles of HFpEF in women. The condition has a relatively high burden of morbidity and mortality, with phenotypic profiles potentially characterizing risk of hospitalization and mortality. Based on limited data, nonpharmacologic and pharmacologic treatments may provide benefit; however, compelling evidence-based, disease-modifying treatments are needed. Many unanswered questions about HFpEF in women warrant further investigation to improve understanding of the disease and provide better patient care.
射血分数保留的心力衰竭（HFpEF）是一种日益普遍的病症，尤其在女性中更为常见。合并症，包括年龄较大、肥胖、糖尿病、高血压和高血脂，是风险因素，并定义了女性 HFpEF 的表型特征。这种疾病具有相对较高的发病率和死亡率负担，其表型特征可能表明住院和死亡的风险。基于有限的数据，非药物和药物治疗可能有益；然而，需要有强有力的循证、改变疾病的治疗方法。关于女性 HFpEF 的许多未解决的问题需要进一步研究，以提高对该疾病的认识并提供更好的患者护理。
