Parizad Razieh, Batta Akash, Hatwal Juniali, Taban-Sadeghi Mohammadreza, Mohan Bishav
Cardiovascular Research Center, Tabriz University of Medical Sciences, Tabriz 51656-87386, Iran.
Department of Cardiology, Dayanand Medical College and Hospital, Ludhiana 141001, Punjab, India.
World J Cardiol. 2025 Apr 26;17(4):104717. doi: 10.4330/wjc.v17.i4.104717.
Heart failure (HF) is a growing public health concern, with an increasing incidence among younger populations. Traditionally, HF was considered a condition primarily affecting the elderly, but of late, emerging evidence hints at a rapidly rising HF incidence in youth in the past 2 decades. HF in youth has been linked to a complex interaction between emerging risk factors, such as metabolic syndrome, environmental exposures, genetic predispositions, and lifestyle behaviors. This review examines these evolving determinants, including substance abuse, autoimmune diseases, and the long-term cardiovascular effects of coronavirus disease 2019, which disproportionately affect younger individuals. Through a comprehensive analysis, the study highlights the importance of early detection, targeted prevention strategies, and multidisciplinary management approaches to address this alarming trend. Promoting awareness and integrating age-specific interventions could significantly reduce the burden of HF and improve long-term outcomes among younger populations.
心力衰竭(HF)是一个日益受到公众关注的健康问题,在年轻人群中的发病率不断上升。传统上,HF被认为是一种主要影响老年人的疾病,但最近有新证据表明,在过去20年中,年轻人中HF的发病率正在迅速上升。年轻人中的HF与新兴风险因素之间的复杂相互作用有关,这些因素包括代谢综合征、环境暴露、遗传易感性和生活方式行为。本综述探讨了这些不断演变的决定因素,包括药物滥用、自身免疫性疾病以及2019冠状病毒病对心血管系统的长期影响,这些因素对年轻人的影响尤为严重。通过全面分析,该研究强调了早期检测、针对性预防策略和多学科管理方法对于应对这一惊人趋势的重要性。提高认识并整合针对特定年龄的干预措施,可以显著减轻HF的负担,并改善年轻人群的长期预后。