Carlson Eric R, Schlieve Thomas
Department of Oral and Maxillofacial Surgery, University of Tennessee Cancer Institute, 1930 Alcoa Highway, Suite 335, Knoxville, TN 37920, USA.
Division of Oral and Maxillofacial Surgery, University of Texas Southwestern Medical School, Parkland Memorial Hospital, 5323 Harry Hines Boulevard, Mail Code 9109, Dallas, TX 75390, USA.
Oral Maxillofac Surg Clin North Am. 2019 Feb;31(1):125-144. doi: 10.1016/j.coms.2018.08.007.
Salivary gland tumors are rare pathologic entities that are derived from major and minor salivary gland tissue located throughout the head and neck region. These tumors are distinctly heterogenous, comprising numerous cell types, especially those deemed malignant. The incidence of malignant salivary gland tumors is widely distributed in both adult and pediatric patient populations. Accurate diagnosis and optimal treatment of these tumors pose challenges to both interpreting pathologists and ablative surgeons. This article examines the epidemiology and pathology of malignant tumors of the major and minor salivary glands and provides recommendations for the most successful treatment approaches.
唾液腺肿瘤是一种罕见的病理实体,起源于分布在头颈部的大、小唾液腺组织。这些肿瘤具有明显的异质性,包含多种细胞类型,尤其是那些被认为是恶性的细胞类型。恶性唾液腺肿瘤的发病率在成人和儿童患者群体中分布广泛。准确诊断和优化治疗这些肿瘤,对病理诊断医师和消融外科医师来说都是挑战。本文探讨了大、小唾液腺恶性肿瘤的流行病学和病理学,并为最成功的治疗方法提供建议。