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唾液腺恶性肿瘤的外科治疗

Surgical treatment of salivary malignant tumors.

作者信息

Lombardi Davide, McGurk Marc, Vander Poorten Vincent, Guzzo Marco, Accorona Remo, Rampinelli Vittorio, Nicolai Piero

机构信息

Department of Otorhinolaryngology - Head and Neck Surgery, University of Brescia, Italy.

Guys and St. Thomas NHS Trust, London, United Kingdom.

出版信息

Oral Oncol. 2017 Feb;65:102-113. doi: 10.1016/j.oraloncology.2016.12.007. Epub 2016 Dec 22.

Abstract

Salivary gland malignant tumors (SGMT) are of key interest for head and neck surgeons since surgery with adjuvant radiotherapy is considered the treatment of choice in most of the cases. Some factors, namely rarity, high histologic heterogeneity, and possible occurrence in all the head and neck subsites, contribute to make this topic very controversial; some unclear aspects pertain surgical treatment. When dealing with major salivary gland malignant tumors (MaSGMT), the most debated issues remain the extent of surgery and management of facial nerve. In minor salivary gland malignant tumors (MiSGMT), conversely, surgical planning is influenced by the specific pattern of growth of the different neoplasms as well as the site of origin of the lesion. Finally, two additional issues, the treatment of the neck (therapeutic or elective) and reconstructive strategy after ablative surgery, are of pivotal importance in management of both MaSGMT and MiSGMT. In this review, we discuss the most relevant and controversial issues concerning surgery of SGMT.

摘要

涎腺恶性肿瘤(SGMT)是头颈外科医生关注的重点,因为在大多数情况下,手术联合辅助放疗被视为首选治疗方法。一些因素,如罕见性、高度的组织学异质性以及可能出现在头颈的所有亚部位,使得这个话题极具争议性;一些不明确的方面与手术治疗有关。在处理大涎腺恶性肿瘤(MaSGMT)时,最具争议的问题仍然是手术范围和面神经的处理。相反,在小涎腺恶性肿瘤(MiSGMT)中,手术规划受不同肿瘤的特定生长模式以及病变起源部位的影响。最后,另外两个问题,即颈部的治疗(治疗性或选择性)和切除术后的重建策略,在MaSGMT和MiSGMT的管理中都至关重要。在本综述中,我们讨论了与SGMT手术相关的最相关和最具争议的问题。

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