（+）-硼内酯的立体选择性合成。
A stereoselective synthesis of (+)-boronolide.
作者信息
Ghosh Arun K, Bilcer Geoffrey
机构信息
Department of Chemistry, University of Illinois at Chicago, 845 West Taylor Street, Chicago, Illinois 60607, USA.
出版信息
Tetrahedron Lett. 2000 Feb 12;41(7):1003-1006. doi: 10.1016/S0040-4039(99)02246-7. Epub 2000 Jun 22.
Abstract
A stereoselective synthesis of (+)-boronolide is described. The key steps involve a stereoselective reduction of an α-hydroxy ketone, allylation of an α-hydroxy aldehyde and a ring-closing olefin metathesis of a homoallylic alcohol derived acrylate ester utilizing Grubbs' catalyst.
摘要
描述了（+）-硼内酯的立体选择性合成。关键步骤包括α-羟基酮的立体选择性还原、α-羟基醛的烯丙基化以及使用格拉布催化剂对源自丙烯酸酯的高烯丙醇进行闭环烯烃复分解反应。
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