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被疑似视神经炎和视网膜中央静脉阻塞掩盖的恶性视神经胶质瘤。

Malignant optic glioma masked by suspected optic neuritis and central retinal vein occlusion.

作者信息

Kalnins Aleksandrs, Penta Mrudula, El-Sawy Tarek, Liao Y Joyce, Fischbein Nancy, Iv Michael

机构信息

Advocate Christ Medical Center, Integrated Imaging Associates, 4440 W 95th St, Oak Lawn, IL 60453, USA.

Division of Neuroradiology, Department of Radiology, Stanford University School of Medicine, 300 Pasteur Drive, Room S-047, Stanford, CA 94305-5105, USA.

出版信息

Radiol Case Rep. 2018 Nov 13;14(2):226-229. doi: 10.1016/j.radcr.2018.10.023. eCollection 2019 Feb.

DOI:10.1016/j.radcr.2018.10.023
PMID:30450148
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6234704/
Abstract

Malignant optic glioma presents a clinical and diagnostic challenge, as early imaging findings overlap with other more common causes of optic nerve enhancement and enlargement, potentially leading to delay in diagnosis. This rare diagnosis carries an extremely poor prognosis, with death usually occurring within 1 year. We present a case of malignant optic glioma that was initially diagnosed as optic neuritis and central retinal vein occlusion, and we emphasize the importance of serial imaging and definitive biopsy to promote early diagnosis and treatment of this entity.

摘要

恶性视神经胶质瘤带来了临床和诊断方面的挑战,因为早期影像学表现与视神经强化和增粗的其他更常见病因重叠,可能导致诊断延迟。这种罕见的诊断预后极差,通常在1年内死亡。我们报告一例最初被诊断为视神经炎和视网膜中央静脉阻塞的恶性视神经胶质瘤病例,并强调连续影像学检查和明确活检对于促进该疾病早期诊断和治疗的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4247/6234704/8185ce22fe5e/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4247/6234704/ca7416c35afc/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4247/6234704/9ce6a8e4df1d/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4247/6234704/388007db679f/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4247/6234704/8185ce22fe5e/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4247/6234704/ca7416c35afc/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4247/6234704/9ce6a8e4df1d/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4247/6234704/388007db679f/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4247/6234704/8185ce22fe5e/gr4.jpg

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World Neurosurg. 2017 Jan;97:751.e1-751.e6. doi: 10.1016/j.wneu.2016.10.083. Epub 2016 Oct 25.
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Clinicopathological and molecular features of malignant optic pathway glioma in an adult.成人恶性视路胶质瘤的临床病理及分子特征
J Clin Neurosci. 2015 Jan;22(1):207-9. doi: 10.1016/j.jocn.2014.05.037. Epub 2014 Aug 21.
3
Diagnosis and management of optic nerve glioma.
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J Clin Neurosci. 2011 Dec;18(12):1585-91. doi: 10.1016/j.jocn.2011.09.003. Epub 2011 Nov 8.
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Br J Ophthalmol. 2010 Jun;94(6):782-3, 812. doi: 10.1136/bjo.2008.137745. Epub 2008 Oct 31.
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J Neuroophthalmol. 2008 Sep;28(3):214-6. doi: 10.1097/WNO.0b013e3181772a36.
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