A basic library of microcomputer programs to obtain immunologically relevant information from protein sequences.

A set of simple and interactive BASIC microcomputer programs which may be used to obtain immunologically relevant information from protein sequences is described. Program listings include the computation of structural dissimilarity between two protein sequences (STRUDIS), the predicted secondary structure (CHOUFAS), their expected degree of three-dimensional similarity by correlation of sequence hydrophobicities (HYDCOR) and the location of alpha-helical segments in the three-dimensional protein structure (HELOC). In addition, a general program is described for running mean calculations (RUNMEAN). All programs are listed in a BASIC version for Apple IIE.