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面向分子生物学家的苹果II Pascal程序。

Apple II PASCAL programs for molecular biologists.

作者信息

Malthiery B, Bellon B, Giorgi D, Jacq B

出版信息

Nucleic Acids Res. 1984 Jan 11;12(1 Pt 2):569-79. doi: 10.1093/nar/12.1part2.569.

Abstract

A collection of PASCAL programs designed for the Apple II microcomputer is presented. These DNA sequence handling and analysis programs are interactive and may be used even by people with no computer experience. The package allows the user to enter a sequence from the keyboard, to modify it, to generate the reverse complement, to create new sequences from parts of other ones, to display or print sequences in various formats. Some analysis tasks are also performed: Translation, searches for restriction sites, for homology with subsequences, either perfect or with an adjustable match percentage. In addition, two programs are also included: The first one allows DNA data sequences generated with a BASIC program under the CP/M operating system to be used with these PASCAL programs. The second one is designed for the automatic assembly of DNA fragments sequences, obtained with the GILBERT-MAXAM or M13 techniques, into a complete sequence.

摘要

本文展示了一组为苹果II微型计算机设计的PASCAL程序。这些DNA序列处理和分析程序是交互式的,即使没有计算机经验的人也可以使用。该软件包允许用户从键盘输入序列、修改序列、生成反向互补序列、从其他序列的部分创建新序列、以各种格式显示或打印序列。还执行一些分析任务:翻译、搜索限制酶切位点、搜索与子序列的同源性,包括完全匹配或具有可调匹配百分比的同源性。此外,还包括两个程序:第一个程序允许在CP/M操作系统下用BASIC程序生成的DNA数据序列与这些PASCAL程序一起使用。第二个程序用于将通过吉尔伯特-马克萨姆或M13技术获得的DNA片段序列自动组装成完整序列。

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引用本文的文献

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2
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Computer analysis of nucleic acid regulatory sequences.核酸调控序列的计算机分析。
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