一个用于绘制蛋白质二级结构的BASIC微型计算机程序。

A BASIC microcomputer program for plotting the secondary structure of proteins.

作者信息

Corrigan A J, Huang P C

出版信息

Comput Programs Biomed. 1982 Dec;15(3):163-8. doi: 10.1016/0010-468x(82)90001-0.

Abstract

An Applesoft BASIC program is presented which allows one to readily graph the secondary structure of a protein on the basis of information derived from its amino acid sequence. This applies the Chou/Fasman rules of predictions to the alpha-helix, beta-sheet and coil conformational parameters. The program produces a first approximation and provides the additional feature which permits specific modification in the plotted structure. These modifications produce a plot comparable to the existing data obtained from X-ray crystallography and manual computations.

摘要

本文介绍了一个苹果软机BASIC程序，该程序可根据蛋白质氨基酸序列信息轻松绘制其二级结构。此程序将周/法斯曼预测规则应用于α螺旋、β折叠和卷曲构象参数。该程序产生初步近似结果，并提供了允许对绘制结构进行特定修改的附加功能。这些修改产生的图形与从X射线晶体学和人工计算获得的现有数据相当。