烟草致癌物研究有助于了解癌症风险并影响政策。
Tobacco carcinogen research to aid understanding of cancer risk and influence policy.
作者信息
Singhavi Hitesh, Ahluwalia Jasjit S, Stepanov Irina, Gupta Prakash C, Gota Vikram, Chaturvedi Pankaj, Khariwala Samir S
机构信息
From the Tata Memorial Centre Mumbai India.
The School of Public Health Brown University Providence Rhode Island U.S.A.
出版信息
Laryngoscope Investig Otolaryngol. 2018 Oct 3;3(5):372-376. doi: 10.1002/lio2.204. eCollection 2018 Oct.
UNLABELLED
Education regarding the health effects associated with tobacco use has made important progress worldwide over the last few decades. Still, tobacco remains a significant cause of cancer and other diseases. As a result, significant worldwide morbidity and mortality is still attributable to tobacco use in modern times. Research into tobacco products, the carcinogens they contain, and how users metabolize them is an important benefit to the advancement of research aimed at reducing harm associated with tobacco use. This review summarizes the use of this type of research to study tobacco users' risk of developing cancer, especially head and neck cancer. In addition, we discuss the use of tobacco research to provide support for increasing levels of federal regulation of tobacco products.
LEVEL OF EVIDENCE
未标注
在过去几十年里，关于烟草使用对健康影响的教育在全球范围内取得了重要进展。然而，烟草仍然是癌症和其他疾病的重要病因。因此，在现代社会，全球范围内仍有大量的发病和死亡可归因于烟草使用。对烟草制品、其所含致癌物以及使用者如何代谢这些致癌物的研究，对于推进旨在减少与烟草使用相关危害的研究具有重要意义。本综述总结了这类研究在探究烟草使用者患癌风险，尤其是头颈癌风险方面的应用。此外，我们还讨论了利用烟草研究为加强联邦对烟草制品的监管力度提供支持的情况。
证据级别
4级。
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