School of Public Health, University of California, Berkeley, California, USA.
Health Econ. 2019 Feb;28(2):280-298. doi: 10.1002/hec.3841. Epub 2018 Nov 18.
The evaluation of policies that are not randomly assigned on outcomes generated by nonlinear data generating processes often requires modeling assumptions for which there is little theoretical guidance. This paper revisits previously published difference-in-differences results of an important example, the introduction of reference pricing to common outpatient procedures, to assess the robustness of the estimated impacts by using different matching, and reweighting techniques to preprocess the data. These techniques improve covariate balance and reduce model dependence. Specifically, we examine the robustness of the effect of reference pricing on patient site-of-care choice, total expenditures, and complication rates. We apply three preprocessing methods: propensity score reweighting, exact matching, and genetic matching. Propensity score reweighting is a technique for achieving covariate balance but does not balance higher-order moments and may lead to bias and inefficiency in estimating treatment effects in the context of nonlinear data generating processes. In contrast, exact matching and genetic matching are designed to balance higher-order moments. We find that although the use of the preprocessing techniques is a valuable robustness check showing that some results are sensitive to the method used, the three approaches generally yield results that do not statistically differ from the published results.
对于非随机分配政策的评估,如果结果是由非线性数据生成过程产生的,通常需要建模假设,而这些假设几乎没有理论指导。本文重新审视了先前发表的一个重要例子的差异分析结果,即参考定价在常见门诊程序中的引入,以使用不同的匹配和重新加权技术来预处理数据,从而评估估计影响的稳健性。这些技术可以改善协变量平衡并降低模型依赖性。具体来说,我们检验了参考定价对患者就诊地点选择、总支出和并发症率的影响的稳健性。我们应用了三种预处理方法:倾向得分重新加权、精确匹配和遗传匹配。倾向得分重新加权是一种实现协变量平衡的技术,但不能平衡更高阶矩,并且在非线性数据生成过程的情况下,可能会导致估计治疗效果的偏差和效率低下。相比之下,精确匹配和遗传匹配是为了平衡更高阶矩而设计的。我们发现,尽管使用预处理技术是一种有价值的稳健性检查,表明某些结果对所使用的方法敏感,但这三种方法通常得出的结果与已发表的结果在统计学上没有差异。