Boehm B, Breuer W, Hermanns W
Institut für Tierpathologie, Ludwig-Maximilians-Universität München, Veterinärstraße 13, 80539 München.
Tierarztl Prax Ausg K Kleintiere Heimtiere. 2011;39(5):305-12.
Odontogenic tumours in the dog and cat, as well as in other domestic animals and in man occur rarely and can be difficult to diagnose. In the present study a great number of canine and feline odontogenic tumours were investigated histopathologically and classified to provide an appropriate basis for the evaluation of these tumours.
In a retrospective study of a total of 1390 canine and 317 feline oral tumours from the years 1977 to 2007, the tumours of odontogenic origin were selected, characterized histopathologically and classified according to the current human WHO-classification of odontogenic tumours (2005) and the current veterinary WHO-classification of odontogenic tumours (2003).
18% (n=250) of the canine and 3.2% (n=10) of the feline oral tumours proved to be of odontogenic origin. They could be divided into benign (epithelial, epithelial and ectomesenchymal, ectomesenchymal) and malignant (carcinomas and sarcomas) odontogenic tumours with a total of 12 different entities. The odontogenic fibroma was the most common canine (n=167) and feline (n=4) odontogenic tumour. The second most common odontogenic tumour for canines was ameloblastoma (n=74) and that for felines was ameloblastic fibroma (n=2). Four of the 12 entities could be classified according to both WHO-classifications of odontogenic tumours. Seven and two of the 12 entities could only be classified according to the current human WHO-classification and veterinary WHO-classification, respectively.
The prognostic evaluation of tumours is of the greatest clinical relevance and calls for an absolutely certain diagnosis. Particularly in the case of the rare and histomorphologically complex odontogenic tumours the current veterinary WHO-classification does not meet this requirement and needs to be revised and extended. The human WHO-classification proved to be more efficient when compared to the veterinary one.
犬、猫以及其他家畜和人类的牙源性肿瘤很少见，且可能难以诊断。在本研究中，对大量犬猫牙源性肿瘤进行了组织病理学研究和分类，以便为评估这些肿瘤提供适当依据。
在一项对1977年至2007年间共1390例犬口腔肿瘤和317例猫口腔肿瘤的回顾性研究中，选取牙源性肿瘤，进行组织病理学特征分析，并根据当前世界卫生组织（WHO）人类牙源性肿瘤分类（2005年）和当前兽医牙源性肿瘤WHO分类（2003年）进行分类。
犬口腔肿瘤中有18%（n = 250）、猫口腔肿瘤中有3.2%（n = 10）被证明是牙源性的。它们可分为良性（上皮性、上皮和外间充质性、外间充质性）和恶性（癌和肉瘤）牙源性肿瘤共12种不同类型。牙源性纤维瘤是最常见的犬（n = 167）和猫（n = 4）牙源性肿瘤。犬的第二常见牙源性肿瘤是成釉细胞瘤（n = 74），猫的是成釉细胞纤维瘤（n = 2）。12种类型中的4种可根据两种WHO牙源性肿瘤分类进行分类。12种类型中分别有7种和2种只能根据当前人类WHO分类和兽医WHO分类进行分类。
肿瘤的预后评估具有最大的临床相关性，需要绝对准确的诊断。特别是对于罕见且组织形态复杂的牙源性肿瘤，当前的兽医WHO分类不符合这一要求，需要修订和扩展。与兽医分类相比，人类WHO分类被证明更有效。
