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白细胞淤滞性视网膜病变:慢性髓性白血病伴严重白细胞增多症的一种不常见的视觉威胁性并发症-病例报告及文献复习。

Leukostasis retinopathy: An uncommon visual threatening complication of chronic myeloid leukemia with severe hyperleukocytosis - A case report and review of the literature.

机构信息

Department of Ophthalmology, Tongji Medical College, Tongji Hospital, Huazhong University of Science and Technology, Wuhan 430030, Hubei, China.

出版信息

Indian J Ophthalmol. 2018 Dec;66(12):1871-1874. doi: 10.4103/ijo.IJO_627_18.

Abstract

To describe a rare case of an unusual visual threatening complication of chronic myeloid leukemia (CML). A 21-year-old male visited the hospital complaining of 1-week painless binocular acute visual loss without any other symptoms. The patient was diagnosed with CML. He then received emergent leukapheresis with imatinib treatment, which achieved obvious hematological remission. However, the visual acuity did not recover along with the CML remission and ocular structure relief. CML-related leukostasis could induce severe leukostasis retinopathy. Hematologists and ophthalmologists should pay more attention to this relatively rare and severe complication of CML.

摘要

描述一例慢性髓性白血病(CML)罕见的视觉威胁性并发症。一名 21 岁男性因无痛性双眼急性视力丧失 1 周而就诊,无其他症状。患者被诊断为 CML。随后,他接受了紧急白细胞分离术和伊马替尼治疗,取得了明显的血液学缓解。然而,视力并没有随着 CML 的缓解和眼部结构的缓解而恢复。CML 相关的白细胞淤滞可引起严重的白细胞淤滞性视网膜病变。血液科医生和眼科医生应更加关注 CML 这种相对罕见且严重的并发症。

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