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阴茎袖带试验能否预测良性前列腺梗阻患者钬激光前列腺剜除术的结局?

Can the Penile Cuff Test Predict the Outcome of Holmium Laser Enucleation of the Prostate for Benign Prostatic Obstruction?

作者信息

Ko Kwang Jin, Na Jun Phil, Lee Munjae, Ryu Gyu Ha, Lee Kyu-Sung

机构信息

Department of Urology, Kangnam Sacred Heart Hospital, Hallym University College of Medicine, Seoul, Republic of Korea.

Department of Urology, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Republic of Korea.

出版信息

Urology. 2019 Feb;124:207-212. doi: 10.1016/j.urology.2018.11.012. Epub 2018 Nov 16.

DOI:10.1016/j.urology.2018.11.012
PMID:30452966
Abstract

OBJECTIVE

To determine whether the penile cuff test can predict surgical outcomes prior to Holmium laser enucleation of the prostate for benign prostatic obstruction.

METHODS

Men scheduled to undergo Holmium laser enucleation of the prostate were enrolled in this study, and all patients underwent the penile cuff test prior to and 3 months after surgery. Patients were categorized as obstructed, nonobstructed, or uncertain by nomogram. Surgical outcomes were assessed by evaluating changes in their international prostate symptom score, quality of life index, and maximum flow rate preoperatively and 3 months postoperatively. The proportion of patients with good outcomes was compared among nomogram-classified groups, and postoperative changes in position on the nomogram were assessed.

RESULTS

A total of 125 patients were analyzed. After surgery, the overall treatment efficacy and symptomatic treatment efficacy were not different between obstructed and nonobstructed patients. However, the maximum flow rate and quality of life score were significantly higher after surgery in obstructed patients compared to nonobstructed patients. After surgery, 75.7% of patients with obstruction and 63.6% of patients categorized as uncertain for obstruction transitioned to the nonobstructed group, while 77.3% of nonobstructed patients remained in the nonobstructed group.

CONCLUSION

The penile cuff test can be used in patients with bladder outlet obstruction to predict good functional outcome and improved quality of life following treatment with Holmium laser enucleation. After Holmium laser enucleation of the prostate, the majority of patients were classified as nonobstructed.

摘要

目的

确定阴茎袖带试验能否在钬激光前列腺剜除术治疗良性前列腺梗阻前预测手术效果。

方法

计划接受钬激光前列腺剜除术的男性纳入本研究,所有患者在手术前及术后3个月均接受阴茎袖带试验。通过列线图将患者分为梗阻组、非梗阻组或不确定组。通过评估术前及术后3个月患者的国际前列腺症状评分、生活质量指数和最大尿流率的变化来评估手术效果。比较列线图分类组中预后良好患者的比例,并评估列线图上术后位置的变化。

结果

共分析125例患者。术后,梗阻组和非梗阻组的总体治疗效果和对症治疗效果无差异。然而,与非梗阻组患者相比,梗阻组患者术后最大尿流率和生活质量评分显著更高。术后,75.7%的梗阻患者和63.6%分类为梗阻不确定的患者转变为非梗阻组,而77.3%的非梗阻患者仍留在非梗阻组。

结论

阴茎袖带试验可用于膀胱出口梗阻患者,以预测钬激光剜除术治疗后良好的功能结局和生活质量改善情况。钬激光前列腺剜除术后,大多数患者被分类为非梗阻。

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