Kojima H, Wang S P, Kuo C C, Grayston J T
Department of Urology, Japanese Red Cross Medical Center, Tokyo.
J Urol. 1988 Sep;140(3):528-31. doi: 10.1016/s0022-5347(17)41710-1.
Etiologic studies including micro-immunofluorescence serology for Chlamydia trachomatis were done on 45 consecutive men with acute epididymitis. Of the men 21, all less than 35 years old, had type specific Chlamydia trachomatis antibody in the semen. All patients with semen antibody also had Chlamydia trachomatis antibody in the serum, while only a few of the patients without semen antibody had serum antibody. Chlamydia antibody titers in the semen specimens were higher than those in the sera and they persisted longer. In only 1 patient with semen antibody was another potential etiological agent for epididymitis demonstrated, while most of the patients without semen antibody had bacterial causes for the epididymitis. It was concluded that measurement of Chlamydia trachomatis antibody in semen offered a noninvasive, sensitive and specific method, useful despite prior antibiotic therapy, for diagnosis of the etiology of epididymitis in young men.
对45例连续的急性附睾炎男性患者进行了病因学研究，包括沙眼衣原体的微量免疫荧光血清学检测。在这些男性患者中，21例年龄均小于35岁，精液中存在型特异性沙眼衣原体抗体。所有精液抗体阳性的患者血清中也有沙眼衣原体抗体，而精液抗体阴性的患者中只有少数有血清抗体。精液标本中的衣原体抗体滴度高于血清中的抗体滴度，且持续时间更长。在仅有1例精液抗体阳性的患者中发现了附睾炎的另一种潜在病因，而大多数精液抗体阴性的患者附睾炎是由细菌引起的。结论是，检测精液中的沙眼衣原体抗体为诊断年轻男性附睾炎的病因提供了一种非侵入性、敏感且特异的方法，即使在先前接受过抗生素治疗的情况下也很有用。
