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[Effect of famine exposure on the risk of chronic disease in later life among population in Harbin].

作者信息

Jin S S, Yu B, Yan S C, Sun W, Cui X M, Zhou X, Yang L Q, Na L X, Guo Y, Bian Z, Li L M, Chen Z M

机构信息

Harbin Medical University, Harbin 150081, China; Nangang District, Harbin Center for Disease Control and Prevention, Harbin 150056, China.

Nangang District, Harbin Center for Disease Control and Prevention, Harbin 150056, China.

出版信息

Zhonghua Liu Xing Bing Xue Za Zhi. 2018 Oct 10;39(10):1314-1318. doi: 10.3760/cma.j.issn.0254-6450.2018.10.005.

Abstract

To study the relations between famine exposure and the risk of chronic diseases as diabetes mellitus, obesity, hypertension, coronary heart disease and stroke in the population of Harbin. Our data was collected from the baseline survey-the China Kadoorie Biobank project (CKB) in Harbin. Retrospective cohort study design was used. Related risks on chronic diseases including diabetes mellitus, obesity, hypertension, coronary heart disease and stroke, were compared among the famine exposed or non-exposed people, respectively by logistic analysis method. After adjusted for factors as age, sex, physical activity, smoking, alcohol intake, diet, family history of diseases, it appeared that the factor 'famine exposure' had increased the risks of diseases as obesity (=1.204, 95: 1.104-1.313, <0.01), hypertension (=1.315, 95: 1.210-1.429, <0.01) and coronary heart disease (=1.495, 95: 1.369-1.632, <0.01). The lower the age of population being exposed to famine, the greater the risk of the development of all kinds of chronic diseases. Famine exposure appeared a risk factor for obesity, hypertension, and coronary heart disease. It is of great significance to ensure the life-long nutrition of the people, especially in the early and adolescent stages, to prevent obesity, hypertension, and coronary heart disease in their later lives.

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