1 Division of Head and Neck Surgery and Communication Sciences, Department of Surgery, Duke University, Durham, North Carolina, USA.
2 Department of Biostatistics and Bioinformatics, Duke University, Durham, North Carolina, USA.
Otolaryngol Head Neck Surg. 2019 Apr;160(4):734-739. doi: 10.1177/0194599818813044. Epub 2018 Nov 20.
Although balloon sinuplasty (BSP) is increasing in popularity, little is known about which patients are the ideal candidates. The objective of this study is to investigate factors that may be associated with BSP failure.
Retrospective review.
Academic center.
This is a 6-year (July 2011-June 2017) retrospective review of patients who underwent BSP or revision endoscopic sinus surgery (rESS) after BSP within a single tertiary health system. Demographics, clinical findings, and radiographic findings were investigated for association with rESS via univariate analyses and a multivariable backward elimination selection procedure.
A total of 154 patients were identified (median age, 53 years): 146 patients underwent BSP at a single health system, with 16 (11%) undergoing rESS; 8 patients underwent BSP at an outside institution and underwent rESS with the senior author. Mean ± SD follow-up was 12.8 ± 16.6 months. Univariate analyses revealed that prior endoscopic sinus surgery, polyps, allergic rhinitis, and gram-negative infection were significantly associated with rESS. As for radiographic findings, a higher Lund-Mackay score, neo-osteogenesis, moderate or complete opacification, and hyperdensities were associated with rESS. The final model after multivariable selection showed that higher radiographic scores (odds ratio, 1.08; 95% CI, 1.01-1.17) and neo-osteogenesis (odds ratio, 5.25; 95% CI, 1.68-16.42) were associated with higher odds for rESS.
This study identifies several clinical and radiographic factors that may be associated with the need for rESS after BSP. Surgeons can take these factors into consideration when deciding whether a patient should forego BSP and undergo conventional FESS.
尽管球囊扩张鼻窦成形术(BSP)越来越受欢迎,但对于哪些患者是理想的候选者知之甚少。本研究旨在探讨可能与 BSP 失败相关的因素。
回顾性研究。
学术中心。
这是一项为期 6 年(2011 年 7 月至 2017 年 6 月)的回顾性研究,研究对象为在单一三级医疗系统内接受 BSP 或 BSP 后行修正内镜鼻窦手术(rESS)的患者。通过单变量分析和多变量向后消除选择程序,研究了与 rESS 相关的人口统计学、临床发现和影像学发现。
共确定了 154 例患者(中位年龄为 53 岁):146 例患者在单一医疗系统中接受 BSP,其中 16 例(11%)行 rESS;8 例患者在外部机构接受 BSP,并由资深作者行 rESS。平均随访时间为 12.8 ± 16.6 个月。单变量分析显示,既往内镜鼻窦手术、息肉、变应性鼻炎和革兰氏阴性感染与 rESS 显著相关。就影像学表现而言,较高的 Lund-Mackay 评分、新骨形成、中度或完全闭塞以及高密度影与 rESS 相关。多变量选择后的最终模型显示,较高的影像学评分(优势比,1.08;95%置信区间,1.01-1.17)和新骨形成(优势比,5.25;95%置信区间,1.68-16.42)与 rESS 的可能性更高相关。
本研究确定了一些可能与 BSP 后需要行 rESS 相关的临床和影像学因素。外科医生在决定患者是否应放弃 BSP 而行传统的 FESS 时,可以考虑这些因素。