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单侧声带麻痹儿童的注射性喉成形术:手术限制和吞咽结局。

Injection Laryngoplasty for Children with Unilateral Vocal Fold Paralysis: Procedural Limitations and Swallow Outcomes.

机构信息

1 Department of Otolaryngology-Head and Neck Surgery, Stanford University, Palo Alto, California, USA.

2 Department of Rehabilitation Services, Lucile Packard Children's Hospital Stanford, Palo Alto, California, USA.

出版信息

Otolaryngol Head Neck Surg. 2019 Mar;160(3):540-545. doi: 10.1177/0194599818813002. Epub 2018 Nov 20.

DOI:10.1177/0194599818813002
PMID:30453837
Abstract

OBJECTIVE

Vocal fold immobility with resultant dysphagia is a known cause of morbidity in the pediatric population. Herein we evaluate the efficacy and adverse events of injection laryngoplasty in children.

STUDY DESIGN

Case series with chart review.

SETTING

Tertiary academic children's hospital.

SUBJECTS AND METHODS

Patients <12 years of age with unilateral vocal fold immobility, dysphagia, and objective swallow study data were included. Primary outcome measures included perioperative adverse events and the ability to advance the diet, as defined by initiation of oral feeds or reduction in thickener following postoperative swallow study.

RESULTS

The mean age of the cohort (N = 41) was 43.83 months (range, 0.5-144 months), and 46.3% of patients were <18 months old. Perioperative adverse events included increased oxygen requirement (n = 3), prolonged operating room time secondary to tenuous cardiopulmonary status (n = 2), and postoperative readmission within 30 days (n = 1). A total of 63.63% (n = 21 of 33) of patients safely advanced their diet following objective improvement on swallow study. Patients undergoing injection laryngoplasty ≤6 months of the onset of vocal fold immobility were more likely to advance their diet following surgery.

CONCLUSION

Injection laryngoplasty has the potential to advance or initiate an oral diet for children with vocal fold immobility, including those in the first months of life. It is relatively free of adverse events, but certain limitations in the pediatric population must be considered. Preoperative characteristics, including timing of injection and premorbidity diet, may guide clinicians in predicting those patients most likely to advance their diet following injection laryngoplasty.

摘要

目的

声带固定导致的吞咽困难是小儿人群发病的已知原因。在此,我们评估了儿童注射式喉成形术的疗效和不良事件。

研究设计

病例系列和图表回顾。

设置

三级学术儿童医院。

受试者和方法

纳入年龄<12 岁、单侧声带固定、吞咽困难和客观吞咽研究数据的患者。主要结局指标包括围手术期不良事件和推进饮食的能力,定义为术后吞咽研究后开始口服喂养或减少增稠剂。

结果

队列(N=41)的平均年龄为 43.83 个月(范围,0.5-144 个月),46.3%的患者<18 个月。围手术期不良事件包括需要增加氧气(n=3)、心肺状况不稳定导致手术时间延长(n=2)和术后 30 天内再次入院(n=1)。吞咽研究客观改善后,共有 63.63%(n=21/33)的患者安全地推进了饮食。声带固定后<6 个月行注射式喉成形术的患者术后更有可能推进饮食。

结论

注射式喉成形术有可能为声带固定的儿童(包括生命最初几个月的儿童)推进或开始口服饮食。它相对没有不良事件,但必须考虑到儿科人群的某些局限性。术前特征,包括注射时间和术前饮食状况,可能有助于指导临床医生预测那些最有可能在注射式喉成形术后推进饮食的患者。

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