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小儿声带麻痹患者吞咽困难的预后

Prognosis of Dysphagia in Pediatric Patients With Vocal Fold Immobility.

作者信息

Georgopoulos Rachel, Arianpour Khashayar, Anne Samantha

机构信息

Head and Neck Institute - Cleveland Clinic, Cleveland, Ohio, USA.

出版信息

Otolaryngol Head Neck Surg. 2025 Sep;173(3):731-737. doi: 10.1002/ohn.1281. Epub 2025 May 5.

Abstract

OBJECTIVE

This study aims to determine the incidence and prognosis of dysphagia in pediatric patients with true vocal fold (TVF) immobility or hypomobility.

STUDY DESIGN

A single-center retrospective chart review.

SETTING

A single-institution tertiary-care center.

METHODS

A total of 89 pediatric patients diagnosed with vocal fold hypo/immobility with a modified barium swallow (MBS) performed were examined. Patient demographic information and etiology of vocal fold immobility as well as laterality were reviewed. Changes in MBS findings over time were assessed.

RESULTS

A total of 89 pediatric patients were identified with a mean follow-up of 35.4 months. The most common etiology of TVF hypo/immobility was cardiothoracic surgery (58.4%).Immobility was observed in 80.6% of patients. Patients with unilateral disease were more likely to present with dysphonia than bilateral disease (40.3% vs 9.1%, odds ratio [OR] 6.75, 95% confidence interval [CI] 1.77-44.5, P = .01). MBS results did not vary statistically with respect to laterality, hypomobility versus immobility, or etiology. Of the 33 children who demonstrated aspiration on their initial MBS, 48.5% demonstrated complete resolution over median of 10.5 weeks. Rates of recovery differed only with respect to hypomobility versus immobility (87.5% vs 33.3%, OR 14.0, 95% CI 2.01-286, P = .0133).

CONCLUSION

Based on the study results, about half of pediatric patients with vocal fold hypo/immobility will have resolution of dysphagia at about 10.5 weeks. This may helpful when deciding on when to obtain follow up imaging/exam on pediatric patients with dysphagia. The only factor that confers improved prognosis is hypomobility when compared to complete immobility.

摘要

目的

本研究旨在确定小儿真性声带(TVF)固定或活动减弱患者吞咽困难的发生率及预后情况。

研究设计

单中心回顾性病历审查。

研究地点

一家单机构三级医疗中心。

方法

共检查了89例经改良钡餐吞咽造影(MBS)诊断为声带活动减弱/固定的小儿患者。回顾了患者的人口统计学信息、声带固定的病因以及病变侧别。评估了MBS检查结果随时间的变化情况。

结果

共确定89例小儿患者,平均随访35.4个月。TVF活动减弱/固定最常见的病因是心胸外科手术(58.4%)。80.6%的患者存在声带固定。单侧病变患者比双侧病变患者更易出现声音嘶哑(40.3%对9.1%,优势比[OR]6.75,95%置信区间[CI]1.77 - 44.5,P = 0.01)。MBS结果在病变侧别、活动减弱与固定、病因方面无统计学差异。在初次MBS检查显示有误吸的33例儿童中,48.5%在中位时间10.5周时显示完全缓解。恢复率仅在活动减弱与固定方面存在差异(87.5%对33.3%,OR 14.0,95% CI 2.01 - 286,P = 0.0133)。

结论

根据研究结果,约一半声带活动减弱/固定的小儿患者在约10.5周时吞咽困难会得到缓解。这在决定何时对吞咽困难的小儿患者进行后续影像学检查/评估时可能会有帮助。与完全固定相比,唯一能改善预后的因素是活动减弱。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4808/12379859/18c4ef8cfd2a/OHN-173-731-g003.jpg

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