Department of Anesthesiology, University of California, San Diego, La Jolla, CA, USA.
Department of Anesthesiology, University of California, San Diego, La Jolla, CA, USA.
Trends Pharmacol Sci. 2018 Dec;39(12):1000-1002. doi: 10.1016/j.tips.2018.10.003.
Management of pain is a fundamental imperative in medicine. Current analgesics suffer from limitations related to efficacy and adverse events of which abuse potential has assumed an important role. Here we highlight the factors that drive the development of novel analgesics and the advances made in the field.
疼痛管理是医学的基本要求。目前的镇痛药存在疗效和不良反应方面的局限性,其中滥用潜力已成为一个重要问题。在这里,我们重点介绍了推动新型镇痛药发展的因素以及该领域的进展。