口腔癌

Oral Cavity Cancer.

作者信息

Ettinger Kyle S, Ganry Laurent, Fernandes Rui P

机构信息

Division of Oral and Maxillofacial Surgery, Department of Surgery, Section of Head and Neck Oncologic Surgery and Reconstruction, Mayo Clinic, Mayo College of Medicine, Mail Code: ro_ma_12_12econ, 200 First Street Southwest, Rochester, MN 55905, USA; Department of Oral and Maxillofacial Surgery, Division of Head and Neck Surgery, University of Florida College of Medicine - Jacksonville, 653-1 West 8th Street 2nd FL/LRC, Jacksonville, FL 32209, USA.

Department of Oral and Maxillofacial Surgery, Division of Head and Neck Surgery, University of Florida College of Medicine - Jacksonville, 653-1 West 8th Street 2nd FL/LRC, Jacksonville, FL 32209, USA; Department of Maxillo-facial, Plastic, Reconstructive and Aesthetic Surgery, Henri Mondor Hospital, 51 avenue du Maréchal de Lattre de Tassigny, Créteil 94010, France.

出版信息

Oral Maxillofac Surg Clin North Am. 2019 Feb;31(1):13-29. doi: 10.1016/j.coms.2018.08.002. Epub 2018 Oct 25.

DOI:10.1016/j.coms.2018.08.002

PMID:30454788

Abstract

Management of oral cavity squamous cell carcinoma has become increasingly driven by emerging evidence as a result of the improved quality of clinical research associating clinicopathologic risk factors with oncologic and survival outcomes. Multiple significant recent changes to treatment guidelines and staging algorithms for oral cavity squamous cell carcinoma reflect evolving understanding of tumor biology and the need for adequately extensive treatment of aggressive disease. This article provides clinicians with a synopsis of the most contemporary management strategies for oral cavity squamous cell carcinoma, framed within the context of historical treatment philosophies.

摘要

随着临床研究质量的提高，将临床病理危险因素与肿瘤学及生存结果相关联的新证据日益增多，口腔鳞状细胞癌的管理也越来越受到其推动。口腔鳞状细胞癌治疗指南和分期算法最近发生的多项重大变化反映了对肿瘤生物学认识的不断演变，以及对侵袭性疾病进行充分广泛治疗的必要性。本文结合历史治疗理念，为临床医生提供了口腔鳞状细胞癌最新管理策略的概述。