Division of Gastroenterology and Hepatology, University of Wisconsin-Madison School of Medicine and Public Health, 1685 Highland Avenue Suite 4000, Madison, WI 53705-2281, USA.
Clin Liver Dis. 2019 Feb;23(1):115-126. doi: 10.1016/j.cld.2018.09.013.
Alcohol-associated cirrhosis (AC) contributes up to 50% of the overall cirrhosis burden in the United States. AC is typically a comorbid condition in association with alcohol-use disorder. AC is often coexistent with other conditions. Several noninvasive methods are available to assist in recognizing the presence of AC. The natural history of AC is governed by the patients continued drinking or abstinence. All treatment starts with abstinence. After decompensation, the progression to acute-on-chronic liver failure heralds death. When patients who have deteriorated are declined liver transplant, palliative care should be considered.
酒精相关性肝硬化（AC）在美国占肝硬化总负担的 50%左右。AC 通常是与酒精使用障碍相关的合并症。AC 常与其他疾病共存。有几种非侵入性方法可用于协助识别 AC 的存在。AC 的自然病程取决于患者是否继续饮酒或戒酒。所有治疗均从戒酒开始。一旦发生失代偿，发展为慢加急性肝衰竭就预示着死亡。当病情恶化的患者被拒绝进行肝移植时，应考虑姑息治疗。
