Division of Liver Diseases, Icahn School of Medicine at Mount Sinai, Recanati-Miller Transplantation Institute, One Gustave Levy Place, Box 1104, New York, NY 10029, USA.
Clin Liver Dis. 2019 Feb;23(1):81-98. doi: 10.1016/j.cld.2018.09.005. Epub 2018 Oct 26.
Alcoholic hepatitis is a unique type of alcohol-associated liver disease characterized by acute liver inflammation caused by prolonged heavy alcohol use. Treatment is mostly supportive. The short-term prognosis of acute alcoholic hepatitis depends on liver recovery, and ranges widely from rapid improvement to grim multiorgan failure despite treatment. Refinement of scoring systems have enhanced prognostication to guide clinical decision making in alcoholic hepatitis. Recent advances in the treatment of alcoholic hepatitis have solidified corticosteroids as the cornerstone of treatment to enhance short-term survival, but not intermediate or long-term survival.
酒精性肝炎是一种独特的与酒精相关的肝病类型，其特征是由于长期大量饮酒引起的急性肝炎症。治疗主要是支持性的。急性酒精性肝炎的短期预后取决于肝脏恢复情况，从迅速改善到尽管治疗仍出现严重多器官衰竭，差异很大。评分系统的改进增强了预后评估，以指导酒精性肝炎的临床决策。酒精性肝炎治疗的最新进展已将皮质类固醇确定为治疗的基石，以提高短期生存率，但不能提高中期或长期生存率。
