State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.
State Key Laboratory of Membrane Biology, Institute of Zoology, Chinese Academy of Sciences, Beijing 100101, China.
J Genet Genomics. 2018 Nov 20;45(11):583-592. doi: 10.1016/j.jgg.2018.09.003. Epub 2018 Nov 3.
Served as a model organism over a century, fruit fly has significantly pushed forward the development of global scientific research, including in China. The high similarity in genomic features between fruit fly and human enables this tiny insect to benefit the biomedical studies of human diseases. In the past decades, Chinese biologists have used fruit fly to make numerous achievements on understanding the fundamental questions in many diverse areas of biology. Here, we review some of the recent fruit fly studies in China, and mainly focus on those studies in the fields of stem cell biology, cancer therapy and regeneration medicine, neurological disorders and epigenetics.
作为一个多世纪以来的模式生物,果蝇极大地推动了包括中国在内的全球科学研究的发展。果蝇与人类在基因组特征上的高度相似性使这种小昆虫能够有益于人类疾病的生物医学研究。在过去的几十年中,中国生物学家已经利用果蝇在理解许多不同生物学领域的基本问题上取得了许多成就。在这里,我们回顾了中国的一些最近的果蝇研究,主要集中在干细胞生物学、癌症治疗和再生医学、神经紊乱和表观遗传学等领域。