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放射肿瘤学为何要开展转化研究?[已修正]

Why should radiation oncology do translational research? [corrected].

作者信息

Cañas Rut, Linares Isabel, Guedea Ferran, Berenguer Miguel Ángel

机构信息

Department of Radiobiology and Cancer, ONCOBELL - IDIBELL, Barcelona, Spain.

Radiation Oncology Department. Institut Català d'Oncologia, L'Hospitalet de Llobregat, Avinguda Granvia, 199-203, 08908, Barcelona, Spain.

出版信息

Rep Pract Oncol Radiother. 2019 Jan-Feb;24(1):60-64. doi: 10.1016/j.rpor.2018.10.008. Epub 2018 Nov 12.

Abstract

Radiological Oncology, like the rest of medical specialties, is beginning to provide can personalized therapies. The ongoing scientific advances enable a great degree of precision in diagnoses and therapies. To fight cancer, from a radiotherapy unit, requires up-to-date equipment, professionals with different specialties working in synchrony (doctors, physicists, biologists, etc.) and a lot of research. Some of the new therapeutic tendencies are immunotherapy, nanoparticles, gene therapy, biomarkers, artificial intelligence, etc. A new clinical paradigm in which new professional networks are inevitable is arising. The mission of translational research is to become a scientific engine in the clinical space.

摘要

放射肿瘤学与其他医学专科一样,正开始提供个性化治疗。不断取得的科学进展使诊断和治疗能够达到很高的精准度。要在放疗科对抗癌症,需要有最新的设备、不同专业的人员协同工作(医生、物理学家、生物学家等)以及大量研究。一些新的治疗趋势包括免疫疗法、纳米颗粒、基因疗法、生物标志物、人工智能等。一种新的临床范式正在出现,在这种范式中,新的专业网络是不可避免的。转化研究的使命是成为临床领域的科学引擎。

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本文引用的文献

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Intraoperative Radiation Therapy (IORT): A Series of 1000 Tumors.术中放射治疗(IORT):1000 例肿瘤系列。
Ann Surg Oncol. 2018 Oct;25(10):2987-2993. doi: 10.1245/s10434-018-6614-3. Epub 2018 Jul 2.
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Nanotechnology Approaches to Improving Cancer Immunotherapy.纳米技术在改善癌症免疫疗法中的应用
Adv Cancer Res. 2018;139:35-56. doi: 10.1016/bs.acr.2018.05.003. Epub 2018 Jun 7.

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