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拉丁美洲某城市中重度睡眠呼吸暂停患者使用持续气道正压通气(CPAP)治疗的情况。

Access to CPAP treatment in patients with moderate to severe sleep apnea in a Latin American City.

作者信息

Nogueira Juan Facundo, Simonelli Guido, Giovini Vanina, Angellotti María Florencia, Borsini Eduardo, Ernst Glenda, Nigro Carlos

机构信息

Instituto Argentino de Investigación Neurológica, Sleep Laboratory - Buenos Aires - Ciudad Autonoma de Buenos Aires - Argentina.

Hospital de Clínicas, University of Buenos Aires, Sleep Laboratory - Buenos Aires - Ciudad Autonoma de Buenos Aires - Argentina.

出版信息

Sleep Sci. 2018 May-Jun;11(3):174-182. doi: 10.5935/1984-0063.20180032.

Abstract

INTRODUCTION

The most effective treatment for moderate to severe obstructive sleep apnea (OSA) is continuous positive airway pressure (CPAP) but adherence may be a limiting factor. Most compliance studies often only include patients under CPAP treatment, neglecting the importance of access to treatment. The aim of this study was to evaluate CPAP access and compliance in OSA patients, after CPAP indication and titration.

METHODS

We included moderate to severe OSA patients, diagnosed by in-lab polysomnography (PSG), with CPAP indication and effective pressure titration. Between 12 to 18 months after treatment was indicated a telephone questionnaire was administered including questions about access to CPAP, reasons of no access, reported adherence and symptoms improvement.

RESULTS

A total of 213 patients responded to the survey (171 males, mean age 53.4±13.5 and BMI 34.02±8.8 kg/m). Almost a third of the patients (28.2%) did not initiate CPAP treatment. Out of 213, 153 patients (71.8%) started treatment with CPAP and 120 (56.3%) reported still being under treatment a year after indication, additionally, 85.8% reported that they were using it =4hs/night. Those who accessed to CPAP were on average, older age, had full coverage of treatment by their medical insurance, required lower effective pressure and experienced more severe sleepiness compared to those individuals who did not accessed to CPAP.

DISCUSSION

A significant proportion of OSA patients with CPAP indication did not initiate and/or eventually abandoned CPAP. Approximately only 50% of the patients were still under treatment, with acceptable self-reported adherence rate and clinical response, one year after the initial treatment indication. Additional measures are necessary to increase access to CPAP and improve long-term compliance.

摘要

引言

对于中度至重度阻塞性睡眠呼吸暂停(OSA),最有效的治疗方法是持续气道正压通气(CPAP),但依从性可能是一个限制因素。大多数依从性研究通常仅纳入接受CPAP治疗的患者,而忽视了获得治疗的重要性。本研究的目的是评估OSA患者在CPAP指征确定和滴定后的CPAP获得情况及依从性。

方法

我们纳入了通过实验室多导睡眠图(PSG)诊断为中度至重度OSA、有CPAP指征且有效压力滴定的患者。在治疗指征确定后的12至18个月,进行了一项电话问卷调查,包括关于获得CPAP的问题、未获得的原因、报告的依从性和症状改善情况。

结果

共有213名患者回复了调查(171名男性,平均年龄53.4±13.5岁,体重指数34.02±8.8kg/m)。近三分之一的患者(28.2%)未开始CPAP治疗。在213名患者中,153名患者(71.8%)开始使用CPAP治疗,120名患者(56.3%)报告在指征确定一年后仍在接受治疗,此外,85.8%的患者报告他们每晚使用CPAP≥4小时。与未获得CPAP的患者相比,获得CPAP的患者平均年龄更大,医疗保险对治疗的覆盖范围更全,所需的有效压力更低,且嗜睡症状更严重。

讨论

相当一部分有CPAP指征的OSA患者未开始和/或最终放弃了CPAP治疗。在初始治疗指征确定一年后,大约只有50%的患者仍在接受治疗,自我报告的依从率和临床反应可接受。需要采取额外措施来增加CPAP的可及性并改善长期依从性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/78fa/6201520/1ac390c49bb2/ssci-11-03-0174-g01.jpg

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