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阻塞性睡眠呼吸暂停的症状与持续气道正压通气的良好依从性有关吗?

Are symptoms of obstructive sleep apnoea related to good continuous positive airway pressure compliance?

作者信息

Kaewkes Chaiwat, Sawanyawisuth Kittisak, Sawunyavisuth Bundit

机构信息

Dept of Medicine, Faculty of Medicine, Khon Kaen University, Khon Kaen, Thailand.

These authors contributed equally.

出版信息

ERJ Open Res. 2020 Sep 28;6(3). doi: 10.1183/23120541.00169-2019. eCollection 2020 Jul.

Abstract

Obstructive sleep apnoea (OSA) is a common disease that can be treated with continuous positive airway pressure (CPAP). CPAP tolerance may be associated with its compliance. Even though there are several predictors for good CPAP compliance, there are limited data available on the correlation between CPAP compliance and OSA symptoms. This study aimed to evaluate this correlation. We conducted a cross-sectional study and enrolled adult patients diagnosed with OSA through polysomnography who had experience using a CPAP machine. A self-report questionnaire was used to evaluate CPAP compliance and study variables. Predictors of CPAP compliance were analysed using stepwise multivariate logistic regression analysis. There were 68 patients with OSA who completed the questionnaire during the study period. Of those, 14 (20.59%) exhibited good CPAP compliance. Only fatigue as a symptom was an independent factor associated with good CPAP compliance, with an adjusted odds ratio of 5.380 (95% CI 1.274-22.719). In conclusion, fatigue was the only symptom associated with good CPAP compliance in patients with OSA.

摘要

阻塞性睡眠呼吸暂停(OSA)是一种常见疾病,可通过持续气道正压通气(CPAP)进行治疗。CPAP耐受性可能与其依从性相关。尽管有多种预测CPAP良好依从性的因素,但关于CPAP依从性与OSA症状之间相关性的数据有限。本研究旨在评估这种相关性。我们进行了一项横断面研究,纳入了通过多导睡眠图诊断为OSA且有使用CPAP机器经验的成年患者。使用自填式问卷评估CPAP依从性和研究变量。采用逐步多因素逻辑回归分析来分析CPAP依从性的预测因素。在研究期间,有68例OSA患者完成了问卷。其中,14例(20.59%)表现出良好的CPAP依从性。仅疲劳这一症状是与良好CPAP依从性相关的独立因素,调整后的优势比为5.380(95%置信区间1.274 - 22.719)。总之,疲劳是OSA患者中与良好CPAP依从性相关的唯一症状。

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