Powerful antibacterial activity of graphene/nanoflower-like nickelous hydroxide nanocomposites.

AIM

The development of new and efficient antibacterial agents is urgent to overcome emerging antimicrobial resistance.

MATERIALS & METHODS: Herein, we have presented a new type of 3D antibacterial system to prompt bacteria to contact with the any plane of nanocomposites.

RESULTS

Comparing the antibacterial activity of graphene oxide, reduced graphene oxide and graphene-loaded nanoflower-like nickelous hydroxide (GN/Ni(OH)) nanocomposites; the GN/Ni(OH) showed stronger bactericidal capability toward Gram-negative/-positive bacteria. Moreover, the GN/Ni(OH) with low cytotoxicity can promote it as 'green' antimicrobial agents. And, the GN/Ni(OH) presented long-term stable antibacterial effectiveness after 2-month storage. The antibacterial mechanisms of GN/Ni(OH) were evidenced as the 3D contact and violent damage to the bacterial structure.

CONCLUSION

The GN/Ni(OH) provides new insights into the antibacterial properties of 3D nanocomposites for effectively fighting pathogen threats in biomedicine and public health.