Hoffmann Michael B, Heinrich Sven P, Thieme Hagen, Al-Nosairy Khaldoon O
Klinik für Augenheilkunde, Universität Magdeburg, Magdeburg.
Center for Behavioral Brain Sciences, Magdeburg.
Klin Monbl Augenheilkd. 2018 Nov;235(11):1229-1234. doi: 10.1055/a-0715-8072. Epub 2018 Nov 20.
Electrophysiological recordings from the retina and cortex are pivotal to reach beyond the retina for ophthalmological and neuro-ophthalmological diagnostic testing. Pattern electroretinograms (PERG) can be used to examine retinal ganglia cells and visual evoked potentials (VEP) help to investigate overall visual pathways. Thus, they support objective functional tests of visual pathways, as well as differential diagnosis. Conventional electrophysiology is of limited value in detecting local defects in the visual field. This gap is filled by applications of multifocal electrophysiology. This permits spatially resolved testing with multifocal PERG (mfPERG) and multifocal VEP (mfVEP), and eventually objective visual field testing with mfVEP. It is important for this spectrum of methods to consider possible confounds when performing the measurements and when interpreting the results. This is explained in the present article on the basis of a series of typical examples.
视网膜和皮层的电生理记录对于超越视网膜进行眼科和神经眼科诊断测试至关重要。图形视网膜电图（PERG）可用于检查视网膜神经节细胞，视觉诱发电位（VEP）有助于研究整体视觉通路。因此，它们支持视觉通路的客观功能测试以及鉴别诊断。传统电生理学在检测视野局部缺陷方面价值有限。多焦点电生理学的应用填补了这一空白。这允许通过多焦点PERG（mfPERG）和多焦点VEP（mfVEP）进行空间分辨测试，并最终通过mfVEP进行客观视野测试。对于这一系列方法而言，在进行测量和解释结果时考虑可能的混杂因素非常重要。本文将基于一系列典型示例对此进行解释。
