Narayanan Sheshadri, Guder Walter G
Department of Pathology, New York Medical College - Metropolitan Hospital Center, New York, NY, 10029, U.S.A.
Institute of Clinical Chemistry, Bogenhausen-Hospital, Munich, Germany.
EJIFCC. 2001 Apr 5;13(1):9-12. eCollection 2001 Apr.
While analytical standards have been developed by established quality control criteria, there has been a paucity in the development of standards for the preanalytical phase. Only recently recommendations have been published regarding the quality of samples including the definition of the optimal sample size, the use of anticoagulants and stabilizers, stability criteria regarding transport and storage and handling of hemolytic, lipemic and icteric samples. Technical recommendations regarding sampling, transport and identification have been developed by national and international consensus organizations. The development of a preanalytical quality manual takes on an urgency in the goal towards achieving total quality control. Every day the laboratory is confronted with data arising out of preanalytical errors. Ability to recognize such data is critical to maintaining total laboratory quality and will be illustrated with case studies.
虽然已经根据既定的质量控制标准制定了分析标准，但分析前阶段的标准制定却很匮乏。直到最近才发布了有关样本质量的建议，包括最佳样本量的定义、抗凝剂和稳定剂的使用、运输和储存的稳定性标准以及溶血、脂血和黄疸样本的处理。国家和国际共识组织已经制定了关于采样、运输和识别的技术建议。制定分析前质量手册对于实现全面质量控制的目标而言变得刻不容缓。实验室每天都会面临分析前误差产生的数据。识别此类数据的能力对于维持实验室整体质量至关重要，本文将通过案例研究加以说明。
