Department of Biochemistry, Samyak Diagnostic Pvt. Ltd, Lalitpur, Nepal.
Department of Pathology, Samyak Diagnostic Pvt. Ltd, Lalitpur, Nepal.
JNMA J Nepal Med Assoc. 2022 Feb 15;60(246):222-224. doi: 10.31729/jnma.6022.
When a sample of an individual is measured at different times at the same or different clinical laboratory, the results are always different, even the state of health of an individual is the same. This disparity in the results from clinical laboratories might confuse diagnosing, treating, and monitoring disease. Patients and healthcare professionals usually interpret these differences as laboratory errors. However, this might not always be the case, because laboratory test results are highly variable and are neither consistent nor comparable due to several reasons other than laboratory error, namely preanalytical variation, biological variation, and analytical variation.
当个体的样本在同一或不同临床实验室的不同时间进行测量时,结果总是不同的,即使个体的健康状况相同也是如此。临床实验室的这些结果差异可能会使疾病的诊断、治疗和监测变得混乱。患者和医疗保健专业人员通常将这些差异解释为实验室错误。然而,情况并不总是如此,因为由于除实验室误差以外的其他原因,实验室检测结果高度可变,既不一致也不可比,这些原因包括分析前变异、生物学变异和分析变异。