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饮食失调对未经治疗的注意力缺陷/多动障碍青年成人社区样本的警觉性和决策的影响。

Eating Disorders Impact on Vigilance and Decision Making of a Community Sample of Treatment Naive Attention-Deficit/Hyperactivity Disorder Young Adults.

作者信息

Nazar Bruno Palazzo, Trindade Amanda Pompeu, Leslie Monica, Malloy-Diniz Leandro Fernandes, Sergeant Joseph, Treasure Janet, Mattos Paulo

机构信息

Institute of Psychiatry, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil.

Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, United Kingdom.

出版信息

Front Psychiatry. 2018 Nov 6;9:531. doi: 10.3389/fpsyt.2018.00531. eCollection 2018.

Abstract

Although impulsivity is suggested as a possible link to explain the association of Attention-Deficit/Hyperactivity Disorder (ADHD) with an Eating Disorder (ED), there is little research on how clinical and cognitive/neuropsychological functioning might change when this comorbidity occurs. ADHD individuals are at a higher of developing ED and also obesity. Some research has described the impact of ADHD in clinical treatment-seeking samples of ED patients. Consequently, we investigated how ED impacted on clinical and cognitive variables of a community sample of treatment-naive ADHD individuals. Ninety college students arranged in three groups (ADHD+ED, ADHD only and Controls) were analyzed using semi-structured interviews for ADHD (K-SADS), the Iowa Gambling Task, the Conner's Continuous Performance Test, Digit and Visual span, as well as rating scales for anxiety (STAI), depression (BDI) and impulsivity (BIS-11), and binge eating (BES). We found that ADHD+ED individuals significantly differed from both groups, presenting with a higher body mass index; more hyperactivity-impulsivity symptoms; higher binge eating scores; more omission errors on the Continuous Performance Test; disadvantageous choices on the Iowa Gambling Task. Also, we demonstrated through a moderation/mediation analysis that a greater level of binge eating mediated the increases in body mass index on our sample. There were no significant paths to explain binge-eating severity through changes on any of the neuropsychological tests used. The presence of an ED in normal weight in a community sample of ADHD individuals is associated with higher body mass index and a worse cognitive functioning.

摘要

尽管冲动性被认为是解释注意力缺陷多动障碍(ADHD)与饮食失调(ED)之间关联的一个可能环节,但关于这种共病发生时临床和认知/神经心理功能可能如何变化的研究却很少。ADHD患者患ED以及肥胖的风险更高。一些研究描述了ADHD对寻求临床治疗的ED患者样本的影响。因此,我们调查了ED如何影响未经治疗的ADHD个体社区样本的临床和认知变量。对90名大学生进行分组(ADHD+ED组、单纯ADHD组和对照组),使用针对ADHD的半结构化访谈(K-SADS)、爱荷华赌博任务、康纳斯连续操作测试、数字和视觉广度测试,以及焦虑评定量表(STAI)、抑郁评定量表(BDI)、冲动性评定量表(BIS-11)和暴饮暴食评定量表(BES)进行分析。我们发现,ADHD+ED个体与其他两组有显著差异,表现为更高的体重指数;更多的多动-冲动症状;更高的暴饮暴食得分;连续操作测试中更多的遗漏错误;在爱荷华赌博任务中做出不利选择。此外,我们通过调节/中介分析表明,更高水平的暴饮暴食介导了我们样本中体重指数的增加。通过所使用的任何神经心理测试的变化,均没有显著路径可以解释暴饮暴食的严重程度。在ADHD个体的社区样本中,正常体重的人患有ED与更高的体重指数和更差的认知功能有关。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d33d/6232382/57940d7d8da1/fpsyt-09-00531-g0001.jpg

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