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本文引用的文献

1
Nanotechnology for surgeons.面向外科医生的纳米技术。
Indian J Surg. 2013 Dec;75(6):485-92. doi: 10.1007/s12262-012-0726-y. Epub 2012 Sep 20.
2
Two-step tunneling technique of deep brain stimulation extension wires-a description.两步式深脑刺激延伸线隧道技术——描述。
Acta Neurochir (Wien). 2013 Dec;155(12):2399-402. doi: 10.1007/s00701-013-1870-2. Epub 2013 Sep 14.
3
One-step tunneling of DBS extensions--a technical note.脑深部电刺激延伸部的一步式隧道技术——一份技术说明。
Acta Neurochir (Wien). 2013 May;155(5):837-40; discussion 840. doi: 10.1007/s00701-013-1667-3. Epub 2013 Mar 7.
4
A phase I trial of deep brain stimulation of memory circuits in Alzheimer's disease.一项关于阿尔茨海默病记忆回路深部脑刺激的 I 期临床试验。
Ann Neurol. 2010 Oct;68(4):521-34. doi: 10.1002/ana.22089.
5
Skin complications in deep brain stimulation for Parkinson's disease: frequency, time course, and risk factors.深部脑刺激治疗帕金森病的皮肤并发症:频率、时间进程和危险因素。
Acta Neurochir (Wien). 2010 Feb;152(2):195-200. doi: 10.1007/s00701-009-0490-3. Epub 2009 Aug 29.
6
Electrical stimulation in anterior limbs of internal capsules in patients with obsessive-compulsive disorder.强迫症患者内囊前肢的电刺激
Lancet. 1999 Oct 30;354(9189):1526. doi: 10.1016/S0140-6736(99)02376-4.
7
Stereotactic treatment of Gilles de la Tourette syndrome by high frequency stimulation of thalamus.通过丘脑高频刺激对抽动秽语综合征进行立体定向治疗。
Lancet. 1999 Feb 27;353(9154):724. doi: 10.1016/s0140-6736(98)05964-9.
8
Combined (thalamotomy and stimulation) stereotactic surgery of the VIM thalamic nucleus for bilateral Parkinson disease.丘脑腹中间核联合(丘脑切开术与刺激)立体定向手术治疗双侧帕金森病
Appl Neurophysiol. 1987;50(1-6):344-6. doi: 10.1159/000100803.
9
Long-term suppression of tremor by chronic stimulation of the ventral intermediate thalamic nucleus.通过长期刺激丘脑腹中间核实现震颤的长期抑制。
Lancet. 1991 Feb 16;337(8738):403-6. doi: 10.1016/0140-6736(91)91175-t.

深部脑刺激装置移位是复发性皮肤糜烂患者的一种解决办法吗?

Is Transposition of Deep Brain Stimulation Device a Solution in Patients with Recurrent Skin Erosions?

作者信息

Servello Domenico, Saleh Christian, Zekaj Edvin

机构信息

Department of Neurosurgery, IRCCS Istituto Ortopedico Galeazzi, Milan, Italy.

出版信息

Asian J Neurosurg. 2018 Oct-Dec;13(4):1252-1253. doi: 10.4103/ajns.AJNS_184_17.

DOI:10.4103/ajns.AJNS_184_17
PMID:30459909
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6208212/
Abstract

Skin erosion and infection are common but serious problems in deep brain stimulation (DBS). They can lead to the removal of the entire DBS device and consequently stop the entire treatment. Of critical importance, therefore, is to find surgical solutions that allow to leave the complex DBS device in place when medical treatment fails in repeated skin complications, to allow continuing treatment in otherwise pharmacological refractory patients. We present a patient with repeated retro-auricular skin erosions, who failed to respond to surgical revisions and antibiotic treatment. However, instead of removing the DBS device as it would be general practice we succeeded with a right to left transposition of connecting cables to save the entire DBS system. There is lack of data on therapeutic surgical options in repeated skin complications. We propose the transposition of DBS device as possible solution for multiple skin erosions in DBS surgery.

摘要

皮肤糜烂和感染是深部脑刺激(DBS)中常见但严重的问题。它们可能导致整个DBS装置被移除,从而使整个治疗中断。因此,至关重要的是找到手术解决方案,以便在反复出现皮肤并发症且药物治疗无效时,能够保留复杂的DBS装置,从而使原本药物难治的患者能够继续接受治疗。我们报告了一名反复出现耳后皮肤糜烂的患者,该患者对手术修复和抗生素治疗均无反应。然而,我们没有像通常那样移除DBS装置,而是成功地将连接电缆从右侧移至左侧,从而挽救了整个DBS系统。目前缺乏关于反复出现皮肤并发症时治疗性手术选择的数据。我们建议将DBS装置移位作为DBS手术中多次皮肤糜烂的一种可能解决方案。